LRRC7 and CDH2

Number of citations of the paper that reports this interaction (PMID 11729199)
18

Data Source:
HPRD (in vitro, in vivo)

		LRRC7	CDH2
Gene Name		leucine rich repeat containing 7	cadherin 2, type 1, N-cadherin (neuronal)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Postsynaptic Density Cell Junction Postsynaptic Membrane	Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Intercalated Disc Integral Component Of Membrane Apical Plasma Membrane Catenin Complex Lamellipodium Synapse Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Beta-catenin Binding Protein Phosphatase Binding Alpha-catenin Binding Gamma-catenin Binding
	Biological Process		Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glial Cell Differentiation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Cell Junction Assembly Adherens Junction Organization Muscle Cell Differentiation Positive Regulation Of MAPK Cascade Cell-cell Adhesion Mediated By Cadherin Cell-cell Junction Organization Blood Vessel Morphogenesis Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Neuronal Stem Cell Maintenance
Pathways			Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Adherens junctions interactions
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666)	Obesity-related traits ( 23251661) Temperament (bipolar disorder) ( 22365631) vWF and FVIII levels ( 21810271)
Protein-Protein Interactions		11 interactors: ACTN2 ACTN4 BAI1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A	22 interactors: ARHGAP32 ARVCF BOC CDH11 CDH4 CDON CREBBP CTNNA1 CTNNB1 CTNND2 EXOC5 FGFR4 GNA12 GNA13 GRIK2 GRIN1 GRIN2D JUP LRRC7 PIK3R1 PKP4 PTPN1
Entrez ID		57554	1000
HPRD ID		09930	00226
Ensembl ID		ENSG00000033122	ENSG00000170558
Uniprot IDs		Q96NW7	A8MWK3 P19022
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transport Regulation Of Protein Localization To Cell Surface Regulation Of Cellular Response To Heat Positive Regulation Of Ion Transport Cell Junction Assembly Cell-cell Junction Organization Synaptic Transmission Cell Adhesion Positive Regulation Of Transport Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Synaptic Transmission Cellular Response To Heat Platelet Degranulation Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Protein Oligomerization Cellular Component Assembly Positive Regulation Of Endocytosis Regulation Of Signaling Response To Heat Establishment Of Localization In Cell Protein Localization To Tight Junction Positive Regulation Of Synaptic Vesicle Endocytosis Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Pinocytosis ER-associated Misfolded Protein Catabolic Process Secretion By Cell Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cellular Response To Interferon-gamma Nuclear Membrane Organization Wound Healing G1/S Transition Of Mitotic Cell Cycle Regulation Of Synaptic Plasticity Regulation Of Synaptic Vesicle Endocytosis Regulation Of Sodium:proton Antiporter Activity Microspike Assembly Peroxisome Proliferator Activated Receptor Signaling Pathway Secretion Response To Interferon-gamma Cellular Localization Regulation Of Relaxation Of Cardiac Muscle Regulation Of Endocytosis Response To Temperature Stimulus Regulation Of Calcium Ion Transport Response To Wounding	Cellular Response To Indole-3-methanol Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Cell Adhesion Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signaling Cell Communication Signal Transduction Multicellular Organismal Development Regulation Of Signal Transduction Positive Regulation Of Muscle Cell Differentiation Anatomical Structure Morphogenesis Cellular Response To Organonitrogen Compound Regulation Of Cell Differentiation Single Organismal Cell-cell Adhesion Developmental Process Response To Organonitrogen Compound Cellular Response To Stimulus Cell Differentiation Anatomical Structure Development Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Muscle Cell Differentiation Response To Stimulus Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Glutamate Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Platelet Activation Neuron-neuron Synaptic Transmission Embryonic Digit Morphogenesis Regulation Of Cell Morphogenesis Regulation Of Neural Precursor Cell Proliferation Locomotion Regulation Of Intracellular Signal Transduction Epithelial Cell-cell Adhesion Cell-cell Junction Assembly Enzyme Linked Receptor Protein Signaling Pathway Axon Development Cell-cell Signaling Vascular Endothelial Growth Factor Receptor Signaling Pathway Homeostatic Process Cellular Component Assembly Protein Heterooligomerization Regulation Of Cell Fate Specification Cellular Response To Peptide Hormone Stimulus Muscle Cell Differentiation Regulation Of MAPK Cascade
Tagcloud ?			bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Difference) ?			bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Intersection) ?