LRRC7

Description		leucine rich repeat containing 7
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Adherens Junction Postsynaptic Density Basolateral Plasma Membrane Specific Granule Lumen Axon Initial Segment Synapse Postsynaptic Membrane
	Molecular Function	Protein Binding Protein Kinase Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Receptor Clustering Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Cell-cell Adhesion Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 21784300) Body mass index ( 24348519) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666) Psoriasis ( 25939698) Type 2 diabetes ( 31049640)
Interacting Genes		18 interacting genes: ACTN2 ACTN4 ADGRB1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 EPS15L1 ERBB2 ERBB3 ERBB4 HOMER3 HOMEZ NQO2 PPP1R9B TOR1A VANGL2
Entrez ID		57554
HPRD ID		09930
Ensembl ID		ENSG00000033122
Uniprot IDs		A0A075B6E9 A0A494C1A4 B1AKT2
PDB IDs
Enriched GO Terms of Interacting Partners?		Postsynaptic Density Cortical Actin Cytoskeleton Regulation Of Cell Communication Regulation Of Signaling Identical Protein Binding Protein Localization To Cell Periphery Regulation Of Protein Localization Peripheral Nervous System Development ERBB3:ERBB2 Complex ERBB2 Signaling Pathway Neuregulin Receptor Activity Basolateral Plasma Membrane Regulation Of Protein Localization To Cell Surface Regulation Of Cellular Localization Calcium- And Calmodulin-dependent Protein Kinase Complex Protein Kinase Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Dendritic Spine Glutamatergic Synapse Cellular Response To Epidermal Growth Factor Stimulus Cell Projection Response To Epidermal Growth Factor Regulation Of Metal Ion Transport Intracellular Protein Localization Synapse Regulation Of Protein Localization To Membrane ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Regulation Of Signal Transduction Anchoring Junction Postsynaptic Actin Cytoskeleton Cell Junction Regulation Of Monoatomic Ion Transport Plasma Membrane Wound Healing Cell Surface Receptor Signaling Pathway ERBB Signaling Pathway Cell Projection Organization Cell Junction Organization Dendrite Regulation Of Transport Neuron Projection Development Synapse Organization Pseudopodium Postsynaptic Density Membrane Schwann Cell Development
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