LRRC7 and CAMK2G

Number of citations of the paper that reports this interaction (PMID 16120608)
37

Data Source:
HPRD (in vitro)

		LRRC7	CAMK2G
Gene Name		leucine rich repeat containing 7	calcium/calmodulin-dependent protein kinase II gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Postsynaptic Density Cell Junction Postsynaptic Membrane	Nucleoplasm Cytosol Plasma Membrane Membrane Endocytic Vesicle Membrane Sarcoplasmic Reticulum Membrane
	Molecular Function	Protein Binding	Calmodulin-dependent Protein Kinase Activity Calcium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Calmodulin Binding ATP Binding Protein Homodimerization Activity
	Biological Process		G1/S Transition Of Mitotic Cell Cycle Calcium Ion Transport Synaptic Transmission Nervous System Development Regulation Of Skeletal Muscle Adaptation Dephosphorylation Cytokine-mediated Signaling Pathway Insulin Secretion Cell Differentiation Cellular Response To Heat Protein Autophosphorylation Protein Oligomerization Regulation Of Calcium Ion Transport Interferon-gamma-mediated Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Relaxation Of Cardiac Muscle
Pathways			Interferon Signaling Cytokine Signaling in Immune system Cellular response to heat stress CREB phosphorylation through the activation of Ras Trafficking of AMPA receptors Interferon gamma signaling HSF1-dependent transactivation Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 21784300) Hypertension risk in short sleep duration ( 22322875) Obesity-related traits ( 23251661) Orofacial clefts ( 22419666)
Protein-Protein Interactions		11 interactors: ACTN2 ACTN4 BAI1 CAMK2A CAMK2G CDH2 CNKSR2 CTNND2 HOMEZ NQO2 TOR1A	31 interactors: ACTN2 ACTN4 ADCY3 ATF1 CABP2 CALM1 CHAT CREM EGFR FLNA GRIA1 GRIA4 GRIN1 GRIN2B LRRC7 MYLK PEA15 PLCB3 PPM1F RCHY1 RRAD RYR1 SMAD2 SMAD3 SMAD4 SPR STAT1 STMN1 SYN1 TH TIAM1
Entrez ID		57554	818
HPRD ID		09930	03672
Ensembl ID		ENSG00000033122	ENSG00000148660
Uniprot IDs		Q96NW7	Q13280 Q13555 Q5SWX3
PDB IDs			2UX0 2V7O
Enriched GO Terms of Interacting Partners?		Regulation Of Ion Transport Regulation Of Protein Localization To Cell Surface Regulation Of Cellular Response To Heat Positive Regulation Of Ion Transport Cell Junction Assembly Cell-cell Junction Organization Synaptic Transmission Cell Adhesion Positive Regulation Of Transport Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Synaptic Transmission Cellular Response To Heat Platelet Degranulation Cell-cell Signaling Positive Regulation Of Ion Transmembrane Transport Adherens Junction Organization Protein Oligomerization Cellular Component Assembly Positive Regulation Of Endocytosis Regulation Of Signaling Response To Heat Establishment Of Localization In Cell Protein Localization To Tight Junction Positive Regulation Of Synaptic Vesicle Endocytosis Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Pinocytosis ER-associated Misfolded Protein Catabolic Process Secretion By Cell Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Cellular Response To Interferon-gamma Nuclear Membrane Organization Wound Healing G1/S Transition Of Mitotic Cell Cycle Regulation Of Synaptic Plasticity Regulation Of Synaptic Vesicle Endocytosis Regulation Of Sodium:proton Antiporter Activity Microspike Assembly Peroxisome Proliferator Activated Receptor Signaling Pathway Secretion Response To Interferon-gamma Cellular Localization Regulation Of Relaxation Of Cardiac Muscle Regulation Of Endocytosis Response To Temperature Stimulus Regulation Of Calcium Ion Transport Response To Wounding	Signaling Cell Communication Synaptic Transmission Cellular Response To Stimulus Cell-cell Signaling Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Cellular Response To Growth Factor Stimulus Neuron-neuron Synaptic Transmission Signal Transduction Response To Growth Factor Response To Abiotic Stimulus Response To Organic Substance SMAD Protein Complex Assembly Cell Development Intracellular Signal Transduction Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Cellular Process Response To Organonitrogen Compound Cell Differentiation Cell Projection Organization Regulation Of Signaling Glutamate Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway System Development Multicellular Organismal Development Neuron Development Regulation Of Synaptic Transmission Platelet Degranulation Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Secretion By Cell Anatomical Structure Morphogenesis Positive Regulation Of Cellular Component Movement Response To Stress Mesenchyme Development Organ Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Import Into Nucleus Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Neurotrophin Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Response To Amphetamine
Tagcloud ?			agouti cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?			agouti cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?