KAT14 and DPPA4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KAT14	DPPA4
Description		lysine acetyltransferase 14	developmental pluripotency associated 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitotic Spindle ATAC Complex	Nucleus Nucleoplasm
	Molecular Function	Histone Acetyltransferase Activity Protein Binding Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups LIM Domain Binding	Chromatin Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Embryonic Development Regulation Of Cell Division Regulation Of Cell Cycle	System Development Lung-associated Mesenchyme Development
Pathways		HATs acetylate histones Formation of WDR5-containing histone-modifying complexes	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Zygotic genome activation (ZGA)
Drugs
Diseases
GWAS		Thyroglobulin plasma levels ( 30929638)	Cardiac hypertrophy ( 21348951) Corneal astigmatism ( 23761726) Metabolite levels ( 23823483)
Interacting Genes		11 interacting genes: ACTC1 CEP70 CSRP2 DPPA4 H3C1 H4C1 H4C16 MBIP TRIM27 TRIM54 ZFY	37 interacting genes: BTBD2 CIRSR CRK DPPA2 EAF1 EIF4A2 EMD FOXR1 GMPPB GRAP GRB2 GTPBP3 HTT INO80B KAT14 LDOC1 MAGOH MAP1LC3A MAP1LC3B MAPK6 MISP NEDD9 OSTF1 PLEKHF2 PTPRO QARS1 RPGRIP1 RPS6KB1 SH3GL1 SH3GL2 SH3GL3 SNX18 SNX33 SPANXN2 TLK1 TNIP1 VIM
Entrez ID		57325	55211
HPRD ID		16765	16836
Ensembl ID		ENSG00000149474	ENSG00000121570
Uniprot IDs		A0A075B6H4 Q9H8E8	Q7L190
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleosome Telomere Organization Nucleosome Assembly Nucleosome Organization Structural Constituent Of Chromatin CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Negative Regulation Of Megakaryocyte Differentiation Protein-DNA Complex Assembly Protein Localization To Chromosome, Centromeric Region Regulation Of Megakaryocyte Differentiation Protein Localization To Chromatin Chromatin Remodeling Protein Heterodimerization Activity Chromosome Organization Chromatin Organization Negative Regulation Of Myeloid Cell Differentiation Protein Localization To Chromosome Actomyosin Structure Organization Organelle Organization Cytoplasmic Actin-based Contraction Involved In Cell Motility Mesenchyme Migration Z Disc	Phosphotyrosine Residue Binding Cytoplasm Protein Binding Cellular Response To Muramyl Dipeptide Cellular Response To Nitrogen Starvation Cleavage Furrow Formation Import Into Cell Endocytosis Central Nervous System Development Phosphatidylethanolamine Binding Plasma Membrane Tubulation Organelle Organization Spindle Pole Centrosome
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?