DANCR and SRSF1

Number of citations of the paper that reports this interaction (PubMedID 31868085)
25

Data Source:
BioGRID (unspecified method)

		DANCR	SRSF1
Description		differentiation antagonizing non-protein coding RNA	serine and arginine rich splicing factor 1
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nuclear Envelope Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function		Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding DNA Topoisomerase Binding RS Domain Binding
	Biological Process		Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA 5'-splice Site Recognition MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Splice Site Recognition MRNA Processing RNA Splicing Signal Transduction Involved In Regulation Of Gene Expression Positive Regulation Of RNA Splicing Protein Localization To Nucleus Regulation Of RNA Splicing MRNA Stabilization Oligodendrocyte Differentiation MRNA Transport Cardiac Muscle Contraction Cellular Response To Interleukin-17 Interleukin-17-mediated Signaling Pathway Liver Regeneration Protein Localization To P-body
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination
Drugs			Copper
Diseases
GWAS			Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
Interacting Genes		20 interacting genes: AP1G2 ARF5 CAV1 EZH2 FOXO1 G3BP2 GLRX3 HNRNPA1 KRT9 NCL NONO PKM PSPC1 RBM25 SERBP1 SRSF1 SYT1 TPM4 YBX1 YBX3	53 interacting genes: AKAP17A APP BCL10 C1QBP CACNA1A CD8A CDC42 CDK12 CDK13 CDK6 CDR1 CLK1 CLK2 CLK3 CLK4 CPSF7 DANCR DIDO1 DYRK1A FOXP1 GEMIN2 HIPK3 HNRNPA0 LNX1 LUC7L LUC7L3 NFYA NXF1 PPARG PRKN PRMT1 PRP4K PRPF4 PSIP1 RNF10 RNPS1 SCAF11 SNRNP70 SREK1 SRPK1 SRPK2 SRSF10 SRSF11 SRSF5 TCERG1 TNPO3 TOP1 TP53 U2AF1 U2AF2 XBP1 YTHDC1 ZRSR2
Entrez ID		57291	6426
HPRD ID			02887
Ensembl ID		ENSG00000226950	ENSG00000136450
Uniprot IDs			Q07955 Q59FA2
PDB IDs			1X4A 2M7S 2M8D 2O3D 3BEG 4C0O 6HPJ 7ABG 8QO9
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding RNA Binding Regulation Of MRNA Metabolic Process Positive Regulation Of Cytoplasmic Translation Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome DNA Topoisomerase Binding Regulation Of Cytoplasmic Translation MRNA Binding Cellular Response To Hyperoxia Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Transport Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Peptide Hormone Stimulus RNA Splicing Regulation Of RNA Splicing Paraspeckles Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Increased Oxygen Levels Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Transport Regulation Of Translation Negative Regulation Of MRNA Catabolic Process Regulation Of RNA Stability RNA Stabilization MRNA Processing Regulation Of Protein Metabolic Process Negative Regulation Of RNA Catabolic Process Response To Hyperoxia Negative Regulation Of Necroptotic Process Negative Regulation Of MRNA Metabolic Process Cellular Response To Chemical Stress Positive Regulation Of Protein Metabolic Process Negative Regulation Of Programmed Necrotic Cell Death Regulation Of Circadian Rhythm Response To Peptide Hormone Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process Regulation Of The Force Of Heart Contraction Negative Regulation Of DNA-templated Transcription MRNA 3'-UTR Binding MRNA Transport	MRNA Metabolic Process RNA Splicing MRNA Processing Nuclear Speck RNA Metabolic Process RNA Processing Nucleic Acid Metabolic Process Regulation Of RNA Splicing Nucleobase-containing Compound Metabolic Process Nucleus Protein-RNA Complex Assembly RNA Binding RNA Splicing, Via Transesterification Reactions Nucleoplasm Regulation Of MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Regulation Of MRNA Processing Protein Serine/threonine Kinase Activity MRNA Splicing, Via Spliceosome Protein Serine Kinase Activity MRNA Splice Site Recognition Nucleic Acid Binding Protein-containing Complex Assembly Regulation Of MRNA Metabolic Process Spliceosomal Complex MRNA Binding Negative Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Assembly Protein-containing Complex Organization Negative Regulation Of RNA Splicing Protein Serine/threonine/tyrosine Kinase Activity Protein Kinase Activity Regulation Of RNA Metabolic Process Regulation Of Gene Expression U2-type Prespliceosome Regulation Of Macromolecule Biosynthetic Process Kinase Activity Regulation Of Primary Metabolic Process Positive Regulation Of Gene Expression Pre-mRNA 3'-splice Site Binding RS Domain Binding U2AF Complex Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Protein Tyrosine Kinase Activity Identical Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?