DANCR and AP1G2

Number of citations of the paper that reports this interaction (PubMedID 31868085)
25

Data Source:
BioGRID (unspecified method)

		DANCR	AP1G2
Description		differentiation antagonizing non-protein coding RNA	adaptor related protein complex 1 subunit gamma 2
Image		No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Endosome Golgi Apparatus Golgi-associated Vesicle Endosome Membrane Membrane Membrane Coat AP-1 Adaptor Complex Transport Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Synapse Intracellular Vesicle
	Molecular Function		Protein Binding Clathrin Adaptor Activity
	Biological Process		Intracellular Protein Transport Golgi To Vacuole Transport Protein Transport Vesicle-mediated Transport
Pathways			Lysosome Vesicle Biogenesis
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Sudden cardiac arrest ( 21658281)
Interacting Genes		20 interacting genes: AP1G2 ARF5 CAV1 EZH2 FOXO1 G3BP2 GLRX3 HNRNPA1 KRT9 NCL NONO PKM PSPC1 RBM25 SERBP1 SRSF1 SYT1 TPM4 YBX1 YBX3	13 interacting genes: AFTPH AP1S1 AP1S2 ATXN1L CENPK DANCR KDM1A NEDD4 PRMT6 RABEP1 SNCA SYNRG XRN1
Entrez ID		57291	8906
HPRD ID			04638
Ensembl ID		ENSG00000226950	ENSG00000213983
Uniprot IDs			O75843 Q86U03 Q86V28
PDB IDs			2E9G 2YMT 3ZHF 4BCX
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding RNA Binding Regulation Of MRNA Metabolic Process Positive Regulation Of Cytoplasmic Translation Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome DNA Topoisomerase Binding Regulation Of Cytoplasmic Translation MRNA Binding Cellular Response To Hyperoxia Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Transport Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Peptide Hormone Stimulus RNA Splicing Regulation Of RNA Splicing Paraspeckles Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Increased Oxygen Levels Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Transport Regulation Of Translation Negative Regulation Of MRNA Catabolic Process Regulation Of RNA Stability RNA Stabilization MRNA Processing Regulation Of Protein Metabolic Process Negative Regulation Of RNA Catabolic Process Response To Hyperoxia Negative Regulation Of Necroptotic Process Negative Regulation Of MRNA Metabolic Process Cellular Response To Chemical Stress Positive Regulation Of Protein Metabolic Process Negative Regulation Of Programmed Necrotic Cell Death Regulation Of Circadian Rhythm Response To Peptide Hormone Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process Regulation Of The Force Of Heart Contraction Negative Regulation Of DNA-templated Transcription MRNA 3'-UTR Binding MRNA Transport	AP-1 Adaptor Complex Endocytosis Clathrin Adaptor Activity Trans-Golgi Network Membrane Protein Transport Import Into Cell Melanosome Assembly Vesicle-mediated Transport Platelet Dense Granule Organization Establishment Of Protein Localization Membrane Coat Cytoplasmic Vesicle Receptor-mediated Endocytosis Cytoplasmic Vesicle Membrane Cellular Localization Terminal Bouton Melanosome Organization Establishment Of Localization In Cell Intracellular Protein Transport Pigment Granule Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Protein Domain Specific Binding Negative Regulation Of Transcription By RNA Polymerase II Formation Of Structure Involved In A Symbiotic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Stem Cell Proliferation Cellular Response To Puromycin Cellular Response To Cycloheximide Histone H2AR3 Methyltransferase Activity Intracellular Protein Localization Secretory Granule Organization Intracellular Transport Clathrin-coated Pit Receptor Internalization Channel Inhibitor Activity Perinuclear Region Of Cytoplasm Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Clathrin-coated Vesicle Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Early Endosome Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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