ATXN7 and LAMB2

Number of citations of the paper that reports this interaction (PMID 21078624)
14

Data Source:
BioGRID (two hybrid)

		ATXN7	LAMB2
Gene Name		ataxin 7	laminin, beta 2 (laminin S)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Microtubule Cytoskeleton Nuclear Matrix	Extracellular Region Basement Membrane Basal Lamina Laminin-3 Complex Extracellular Matrix Laminin-11 Complex Synapse Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Protein Binding	Integrin Binding Structural Molecule Activity
	Biological Process	Microtubule Cytoskeleton Organization Chromatin Organization Transcription, DNA-templated Nucleus Organization Visual Perception Histone Deubiquitination Negative Regulation Of Phosphorylation Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter	Cell Adhesion Axon Guidance Neuromuscular Junction Development Visual Perception Astrocyte Development Schwann Cell Development Extracellular Matrix Organization Axon Extension Involved In Regeneration Retina Development In Camera-type Eye Metanephric Glomerular Visceral Epithelial Cell Development Metanephric Glomerular Basement Membrane Development
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones	Laminin interactions ECM proteoglycans Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		59 interactors: ACTN1 ACTN2 ACTN4 ADAM33 AGRN CARD10 CEP70 CEP72 COG6 CRIM1 CRX EFEMP1 EFEMP2 FBN1 FN1 GOLGA2 GOLGA3 GPRASP1 GRN HIST1H3A JAG2 KALRN KAT2A LAMB1 LAMB2 LRSAM1 LTBP4 MATN2 MEGF6 MPRIP NELL1 NELL2 NOC2L NUP62 PICK1 PNMA1 PPP1R12C PSMC1 RABEP1 RAD23A RNF31 SIAH1 SNX1 SPRY1 SSFA2 SUMO1 SUMO2 TAF10 THY1 TP53BP2 TRAF2 TRIM23 TRIM27 TRIM54 TRRAP TXNDC11 UBQLN2 VCP VWF	8 interactors: ATXN7 KPNA2 ORC5 PIK3R2 PLEKHA5 RBL1 STAT3 ZNF512B
Entrez ID		6314	3913
HPRD ID		06365	01034
Ensembl ID		ENSG00000163635	ENSG00000172037
Uniprot IDs		O15265 Q9UPD8	P55268
PDB IDs		2KKR
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Response To Stimulus Cell-substrate Junction Assembly Cell-substrate Adhesion Platelet Degranulation Cellular Localization Protein Modification By Small Protein Conjugation Regulation Of Proteolysis Vesicle-mediated Transport Regulation Of Protein Metabolic Process Establishment Of Localization In Cell Cell Junction Assembly Protein Localization To Tight Junction Regulation Of Metabolic Process Histone Deubiquitination Regulation Of Cellular Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Apoptotic Process Cellular Response To Stimulus Regulation Of Cellular Protein Metabolic Process Response To Wounding Regulation Of Protein Catabolic Process Regulation Of Cell Death Protein Ubiquitination Protein Polyubiquitination Blood Coagulation Cellular Protein Modification Process Hemostasis Positive Regulation Of Proteolysis Focal Adhesion Assembly Cellular Component Assembly Protein Localization Extracellular Matrix Disassembly Platelet Activation Regulation Of Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Protein Complex Assembly Regulation Of Signaling Cellular Protein Metabolic Process Protein Localization To Cell Junction Cell Death Death Response To Stress Nervous System Development Positive Regulation Of Protein Catabolic Process Secretion By Cell Substrate Adhesion-dependent Cell Spreading Adherens Junction Assembly Protein Metabolic Process	Regulation Of Lipid Kinase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Viral Process Protein Import Into Nucleus Nuclear Import Cellular Response To Growth Factor Stimulus Response To Growth Factor Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Protein Import Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Protein Localization To Nucleus Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Glucose Homeostasis Cellular Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Neurotrophin Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Nitrogen Compound Metabolic Process Negative Regulation Of Glycolytic Process Cellular Macromolecule Biosynthetic Process Radial Glial Cell Differentiation Macromolecule Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Lipid Metabolic Process Transcription, DNA-templated Cellular Response To Peptide Hormone Stimulus Interleukin-6-mediated Signaling Pathway Cellular Response To Peptide RNA Biosynthetic Process Establishment Of Protein Localization To Organelle Response To Organic Substance Regulation Of Transcription, DNA-templated Histone Deubiquitination Positive Regulation Of Cellular Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process NLS-bearing Protein Import Into Nucleus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation
Tagcloud ?		accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Difference) ?		accounts asian ataxia ataxias atn1 atxn1 atxn2 atxn3 cag caucasians causal causative consortium ethnic expanded expansions explained geographical htt influenced modifier polyglutamine quadratic reflected replicated sister spinocerebellar tbp variability
Tagcloud (Intersection) ?