PSMD4 and SIAH2

  • Number of citations of the paper that reports this interaction (PMID 22350919)
  • 1
  • Data Source:
  • BioGRID (enzymatic study)

PSMD4

SIAH2

Gene Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 siah E3 ubiquitin protein ligase 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 41 interactors: ADRM1 APP BTRC CCNA2 CCNB1 COPS2 COPS7A CUL1 EGFR ELSPBP1 FBXO25 FLOT1 GNB5 ID1 MDM2 MYOD1 NEDD4 NEDD4L NEDD8 NUB1 NUPR1 PARK2 PSMC2 RAD23A RAD23B RASSF8 RBCK1 SCHIP1 SIAH2 SREBF2 STUB1 TCF3 TRIM63 UBB UBC UBE2C UBE3A UBQLN1 UBQLN2 UBQLN4 XPC 39 interactors: AFF1 ATN1 CACYBP CCBE1 DCC DYRK2 EEF1D EGLN3 HIPK2 HIPK3 MYD88 OPRM1 PEG10 PEG3 PIAS1 PIAS2 PIAS3 PML POU2AF1 PSMD4 RBBP8 SETD2 SNCA SNCAIP SPRY2 STAT3 SYP TINF2 TP53BP2 TPX2 TRAF2 UBE2D1 UBE2D2 UBE2D3 UBE2I UBE2L6 USP13 USP19 VAV1
Entrez ID 5710 6478
HPRD ID 03386 03737
Ensembl ID ENSG00000159352 ENSG00000181788
Uniprot IDs P55036 Q5VWC4 O43255
PDB IDs 1P9C 1P9D 1UEL 1YX4 1YX5 1YX6 2KDE 2KDF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
confirm  degradation  demonstrating  dominant  e3  exploited  extend  incorporated  interacting  interferring  ligase  mdm2  modulate  motifs  p53  participates  proteasomal  proteasome  recognition  rescue  rpn10  s5a  selectively  selectivity  stabilization  ubiquitin  ubiquitinated  uim  uims 
adding  complexity  decisions  determines  e3  fail  fate  favoring  feedback  finger  hipk2  homeodomain  inactivated  interferes  ligase  loop  preferentially  proline  stimulates  switch  termination  ubiquitin  ubiquitination  uncovers  waf1  xaf1  xiap  zinc  znf313 
Tagcloud (Difference) ?
confirm  degradation  demonstrating  dominant  exploited  extend  incorporated  interacting  interferring  mdm2  modulate  motifs  p53  participates  proteasomal  proteasome  recognition  rescue  rpn10  s5a  selectively  selectivity  stabilization  ubiquitinated  uim  uims 
adding  complexity  decisions  determines  fail  fate  favoring  feedback  finger  hipk2  homeodomain  inactivated  interferes  loop  preferentially  proline  stimulates  switch  termination  ubiquitination  uncovers  waf1  xaf1  xiap  zinc  znf313 
Tagcloud (Intersection) ?
e3  ligase  ubiquitin