PLSCR3 and TRIP13

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		PLSCR3	TRIP13
Gene Name		phospholipid scramblase 3	thyroid hormone receptor interactor 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Mitochondrial Membrane	Male Germ Cell Nucleus Nucleus
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Calcium-dependent Protein Binding	Transcription Cofactor Activity Protein Binding ATP Binding Identical Protein Binding
	Biological Process	Apoptotic Process Phospholipid Scrambling Glucose Homeostasis Cholesterol Homeostasis Cellular Response To Lipopolysaccharide	Oocyte Maturation Double-strand Break Repair Transcription From RNA Polymerase II Promoter Synaptonemal Complex Assembly Reciprocal Meiotic Recombination Male Meiosis I Female Meiosis I Spermatogenesis Spermatid Development Oogenesis Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CATSPER1 PLSCR1 PRKCD STK16 TRIP13	75 interactors: ADAM15 AMDHD2 ARL11 ARSA ASB13 C11orf54 C4orf33 CARD14 CCBL1 CD99 COMT CPSF3L CRMP1 CRYBA2 CYB5R2 DDAH2 DIP2A DPYSL4 DTX2 FNDC3B GALT GLYCTK GPRIN2 GPSM1 HDHD3 KRTAP12-1 KRTAP12-2 KRTAP26-1 KRTAP3-2 LASP1 LNX1 LOXL4 LRR1 LRRC61 M1AP MAD2L1BP MAD2L2 METTL15 MGAT5B MORN3 MPPED2 MVP NIF3L1 NME4 PARK2 PARP11 PBLD PCMTD2 PELI1 PLAC8 PLK3 PLSCR3 PLSCR4 PPP2CA QARS RBPMS RHOXF2 SCP2 SEC24A SELENBP1 SEMA4G SIGLEC5 SMUG1 SPRYD7 STAMBP STAMBPL1 TEX37 THRB TINAGL1 TLDC1 TNRC6A TPT1 WDYHV1 ZNF34 ZNF655
Entrez ID		57048	9319
HPRD ID		07400	05145
Ensembl ID		ENSG00000187838	ENSG00000071539
Uniprot IDs		Q9NRY6	Q15645
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Transcription From RNA Polymerase II Promoter Interleukin-10 Production Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Platelet Activation Negative Regulation Of Filopodium Assembly Interleukin-12 Production Positive Regulation Of Ceramide Biosynthetic Process Phosphatidylserine Biosynthetic Process Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Peptidyl-tyrosine Phosphorylation Regulation Of Ceramide Biosynthetic Process Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Glial Cell Apoptotic Process Gene Expression Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phospholipid Scrambling Positive Regulation Of Cellular Biosynthetic Process Regulation Of Superoxide Anion Generation Female Meiosis I Regulation Of Microtubule-based Movement Blood Coagulation Hemostasis Regulation Of Platelet Aggregation Negative Regulation Of Platelet Activation Fusion Of Sperm To Egg Plasma Membrane Regulation Of Cell Activation Plasma Membrane Fusion Response To Interferon-beta Positive Regulation Of Protein Dephosphorylation Spermatogenesis Male Gamete Generation Neutrophil Activation Synaptonemal Complex Assembly Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Synaptonemal Complex Organization Oocyte Maturation Positive Regulation Of Lipid Catabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Phosphatidylserine Metabolic Process Wound Healing Response To Growth Factor Regulation Of Platelet Activation Cellular Senescence	Negative Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Stem Cell Differentiation Catabolic Process Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phospholipid Scrambling Regulation Of Epithelial To Mesenchymal Transition Metabolic Process Endomembrane System Organization Regulation Of SMAD Protein Import Into Nucleus Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Phosphorylation Phospholipid Transport Carboxylic Acid Catabolic Process Negative Regulation Of Protein Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Morphogenesis Involved In Differentiation Negative Regulation Of Programmed Cell Death Dopamine Metabolic Process Regulation Of Protein Autophosphorylation Positive Regulation Of Homocysteine Metabolic Process RRNA Base Methylation Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Glutaminyl-tRNA Aminoacylation Lipid Hydroperoxide Transport Positive Regulation Of Intracellular Cholesterol Transport UDP-glucose Catabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To Phosphate Starvation Male Meiosis Chromosome Separation Regulation Of Protein Metabolic Process Negative Regulation Of Cell Death Negative Regulation Of Phosphorylation Protein Ubiquitination Regulation Of Apoptotic Process
Tagcloud ?		abss alg associating bromopalmitate centrifugation ceramide disassembling dispensable e235q enlarged escrt exosomal exosomes fused gfp gw4869 hek names palmitoylated palmitoylation phospholipid q79l rab5a scramblases scrambling transferable vps4b	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Difference) ?		abss alg associating bromopalmitate centrifugation ceramide disassembling dispensable e235q enlarged escrt exosomal exosomes fused gfp gw4869 hek names palmitoylated palmitoylation phospholipid q79l rab5a scramblases scrambling transferable vps4b	abrogates anaphase apc assembles attached bub3 bubr1 cdc20 centrally checkpoint comet correctly cyclosome delays disassemble disassembled disassembly hela hydrolysis inactivated mad2 mcc mitotic p31 participates spindle subcomplex sufficiently turned
Tagcloud (Intersection) ?