PLSCR3 and LCE2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR3	LCE2B
Description		phospholipid scramblase 3	late cornified envelope 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Cytosol Plasma Membrane Membrane Mitochondrial Membrane
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Lead Ion Binding Mercury Ion Binding Calcium-dependent Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Lipid Transport Apoptotic Process Mitochondrial Membrane Organization Plasma Membrane Phospholipid Scrambling Glucose Homeostasis Cholesterol Homeostasis Regulation Of Apoptotic Process Cellular Response To Lipopolysaccharide Regulation Of Release Of Cytochrome C From Mitochondria	Epidermis Development Keratinization
Pathways			Formation of the cornified envelope
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		34 interacting genes: ACTMAP AIPL1 C10orf55 C22orf39 CATSPER1 COL8A1 HOXA1 INCA1 KRTAP11-1 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP3-2 KRTAP3-3 KRTAP6-1 LCE1C LCE2B LCE4A LCE5A MAPKBP1 NAA10 NXPE2 PITX1 PLSCR1 PRKCD RUNX1T1 S100A7L2 SMCP STK16 TNIP3 TNS2 TRIP13 WWOX ZIC1	78 interacting genes: ADAMTSL4 CRCT1 CYSRT1 DHRS1 GRN GUCD1 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE4A LCE5A MDFI NBPF19 NECTIN2 NOTCH2NLA NR4A3 NUFIP2 OTX1 PLA2G10 PLAC8 PLSCR3 PLSCR4 RGS17 RGS20 RNF4 SPRED2 SPRY3 TGFB1 TRIM42 TSPAN4 VASN
Entrez ID		57048	26239
HPRD ID		07400	17260
Ensembl ID		ENSG00000187838	ENSG00000159455
Uniprot IDs		Q9NRY6	O14633
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Hair Cycle Identical Protein Binding Protein Binding Cytosol
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