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PMEPA1 and UBQLN4
Number of citations of the paper that reports this interaction (PMID
16713569
)
214
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PMEPA1
UBQLN4
Gene Name
prostate transmembrane protein, androgen induced 1
ubiquilin 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Plasma Membrane
Endosome Membrane
Integral Component Of Membrane
Early Endosome Membrane
Nucleus
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Nuclear Proteasome Complex
Cytosolic Proteasome Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
WW Domain Binding
R-SMAD Binding
Protein Binding
Polyubiquitin Binding
Identical Protein Binding
Biological Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of SMAD Protein Complex Assembly
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Androgen Receptor Signaling Pathway
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Loss of Function of TGFBR2 in Cancer
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
Downregulation of TGF-beta receptor signaling
SMAD2/3 MH2 Domain Mutants in Cancer
TGFBR1 KD Mutants in Cancer
TGF-beta receptor signaling activates SMADs
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Response to fenofibrate (adiponectin levels) (
23149075
)
Inflammatory bowel disease (
23128233
)
Protein-Protein Interactions
2 interactors:
NEDD4
UBQLN4
157 interactors:
ADAM33
ADPGK
AGR2
ANKRD13D
AREG
ARL4C
ATPIF1
ATXN1
BAG6
BPIFA1
C11orf49
C1orf94
C1QTNF1
CACNA1G
CCDC107
CCDC134
CCDC136
CCDC14
CCDC33
CCL21
CD99
CDSN
CEND1
COL8A1
COPB1
CPSF6
CRIPT
CSTF2
CSTF2T
CTSB
CYB5R1
DAZAP2
DKK3
DMPK
DNAJB11
DTX2
EAPP
EDN1
EEF1A1
EFEMP2
ELF5
EPDR1
ERP27
ERP29
FA2H
FGFBP1
FKBP2
FKBP7
FZD7
GABRD
GDI1
GKAP1
GPX7
HAVCR1
HGS
HK2
HSPA13
HSPA5
IGFBP6
IGHM
IGLC1
IMMT
IMPDH2
ITPRIPL1
KLHL26
KLHL42
LAT2
MDK
MDM2
MIEF2
MIF4GD
MLLT6
MOAP1
MYDGF
NAE1
NME3
NOMO1
NOMO3
NOTCH2NL
NPHP1
NPPA
NXF1
OAT
ORC5
PBXIP1
PCDH17
PCDH8
PDIA5
PDLIM7
PELI2
PICK1
PIN1
PIP4K2B
PLA2G16
PMEPA1
PNMA1
PPIB
PPIC
PRL
PRPF40A
PSMD4
PTN
PTPRN
PTPRN2
QSOX1
RAD23A
RAI2
RBM10
RIC8A
RNF11
RNPS1
ROBO2
RPN1
RSRC2
RUNX1T1
RXRA
SCAF1
SCG2
SCG5
SCMH1
SEMG1
SERPINE1
SERPINH1
SERPINI2
SMAD3
SMAD9
SMARCB1
SPAG8
SPINT1
SPP1
SRGN
SRSF2
STAM2
STMN1
SUPT20H
TFF1
TGFB1I1
TNFRSF14
TNRC6B
TRAF2
TRIB2
TRIM32
UBQLN1
UBQLN2
UBR7
UNC119
UROS
USMG5
VIP
WAC
YWHAQ
ZBTB22
ZDHHC3
ZFPM2
ZG16
ZG16B
ZNF205
Entrez ID
56937
56893
HPRD ID
09415
05670
Ensembl ID
ENSG00000124225
ENSG00000160803
Uniprot IDs
Q5JY37
Q969W9
B4DZF6
Q9NRR5
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transmission Of Virus
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Development Involved In Symbiotic Interaction
Regulation Of Protein Catabolic Process
Progesterone Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Glucocorticoid Receptor Signaling Pathway
Protein Targeting To Lysosome
Negative Regulation Of Sodium Ion Transport
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein Localization To Lysosome
Receptor Catabolic Process
Protein Targeting To Vacuole
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Establishment Of Protein Localization To Vacuole
Regulation Of Potassium Ion Transmembrane Transporter Activity
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Endocardial Cushion Development
Regulation Of Potassium Ion Transmembrane Transport
Protein Monoubiquitination
Receptor Internalization
Lysosomal Transport
Neuromuscular Junction Development
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cellular Response To UV
Regulation Of Potassium Ion Transport
Outflow Tract Morphogenesis
Regulation Of Sodium Ion Transport
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Dendrite Morphogenesis
Intracellular Steroid Hormone Receptor Signaling Pathway
Vacuolar Transport
Receptor Metabolic Process
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Synapse Organization
Regulation Of Synapse Structure Or Activity
Cellular Response To Light Stimulus
Negative Regulation Of Ion Transport
Interaction With Host
Regulation Of Protein Metabolic Process
Regulation Of Dendrite Development
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Positive Regulation Of Nucleocytoplasmic Transport
Response To Calcium Ion
Response To UV
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cellular Response To Radiation
Regulation Of Cellular Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Signaling
Signal Transduction
Cell Communication
Regulation Of Protein Metabolic Process
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Stimulus
Multicellular Organismal Development
Positive Regulation Of Metabolic Process
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Cell Proliferation
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transport
Organ Development
Positive Regulation Of Mitochondrion Organization
Regulation Of Cellular Localization
Regulation Of Proteolysis
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Developmental Process
Response To Organic Substance
Tissue Development
Regulation Of Metabolic Process
Positive Regulation Of Gene Expression
Anatomical Structure Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Signal Transduction
Regulation Of Cellular Response To Growth Factor Stimulus
Regulation Of Behavior
Regulation Of Phosphorus Metabolic Process
System Development
Protein Peptidyl-prolyl Isomerization
Regulation Of Signaling
Negative Regulation Of Cell Proliferation
Regulation Of Body Fluid Levels
Regulation Of Chemotaxis
Cell Surface Receptor Signaling Pathway
Regulation Of Phosphorylation
Cellular Localization
Defense Response
Regulation Of Mitochondrion Organization
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Cellular Component Organization
Tagcloud
?
aa
african
american
androgen
ar
aza
cap
capture
caucasian
contributing
cpg
cutting
decitabine
deoxycytidine
dissected
e3
embedded
focuses
frozen
intronic
inverse
methylation
methyltransferase
micro
optimum
prostate
qrt
restores
tumorigenesis
Tagcloud (Difference)
?
aa
african
american
androgen
ar
aza
cap
capture
caucasian
contributing
cpg
cutting
decitabine
deoxycytidine
dissected
e3
embedded
focuses
frozen
intronic
inverse
methylation
methyltransferase
micro
optimum
prostate
qrt
restores
tumorigenesis
Tagcloud (Intersection)
?