THAP10 and DYNLL2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		THAP10	DYNLL2
Description		THAP domain containing 10	dynein light chain LC8-type 2
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Microtubule Associated Complex Plasma Membrane Cilium Postsynaptic Density Microtubule Cytoskeleton Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Scaffold Protein Binding
	Biological Process		Microtubule-based Process
Pathways			Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)	Blood protein levels ( 30072576)
Interacting Genes		13 interacting genes: CCNDBP1 DYNLL1 DYNLL2 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 NME7 PLEKHF2 PSME3 PTS	30 interacting genes: BMF C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HOMER3 IHO1 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 REDIC1 SKAP1 SMCP SPAG8 THAP10 TPPP XIAP ZAR1
Entrez ID		56906	140735
HPRD ID		15497	06489
Ensembl ID		ENSG00000129028	ENSG00000264364
Uniprot IDs		Q9P2Z0	Q96FJ2
PDB IDs			2XQQ 3P8M 4D07 7CNU
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Cytosol Cytoplasmic Dynein Complex Dynein Intermediate Chain Binding Dynein Complex Microtubule Associated Complex 6-pyruvoyltetrahydropterin Synthase Activity Ciliary Tip Intraciliary Transport Cilium Primary Ureteric Bud Growth Myosin V Complex Identical Protein Binding Centrosome Scaffold Protein Binding Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Deoxyribonuclease Inhibitor Activity Microtubule Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Proteasome Activator Complex Microtubule-based Process	Microtubule Binding
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