THAP10 and PTS

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		THAP10	PTS
Gene Name		THAP domain containing 10	6-pyruvoyltetrahydropterin synthase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Mitochondrion Cytosol
	Molecular Function	DNA Binding Metal Ion Binding	6-pyruvoyltetrahydropterin Synthase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process		Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development Small Molecule Metabolic Process Nitric Oxide Metabolic Process Regulation Of Nitric-oxide Synthase Activity
Pathways			Metabolism of nitric oxide eNOS activation and regulation Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CCNDBP1 DYNLL2 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP4-12 LZTS2 PTS	12 interactors: ATM ATR COIL FNDC5 FXR2 LNX1 PBRM1 PRKDC PRKG2 SDCBP THAP10 WDYHV1
Entrez ID		56906	5805
HPRD ID		15497	11840
Ensembl ID		ENSG00000129028	ENSG00000150787
Uniprot IDs		Q9P2Z0	Q03393
PDB IDs			3I2B
Enriched GO Terms of Interacting Partners?		Synaptic Target Recognition Tetrahydrobiopterin Biosynthetic Process Spindle Midzone Assembly Microtubule Severing Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Pteridine-containing Compound Biosynthetic Process Microtubule-based Process Neuron Recognition Regulation Of Protein Localization Regulation Of Nitric-oxide Synthase Activity	Peptidyl-serine Phosphorylation Response To Gamma Radiation Double-strand Break Repair Via Homologous Recombination Recombinational Repair Replicative Senescence Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Signal Transduction By P53 Class Mediator Response To Ionizing Radiation DNA Damage Checkpoint Double-strand Break Repair Cellular Response To Gamma Radiation V(D)J Recombination Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Response To Heat Protein Autophosphorylation Cell Cycle Checkpoint DNA Recombination Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Cellular Protein Metabolic Process Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cellular Response To Ionizing Radiation Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To Heat Negative Regulation Of Protein Metabolic Process Positive Regulation Of Response To DNA Damage Stimulus Cell Aging Telomere Maintenance Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Peptidyl-amino Acid Modification Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Somitogenesis Cell Cycle Process Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Radiation Somite Development Mitotic DNA Damage Checkpoint Cellular Protein Modification Process Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle B Cell Differentiation Response To Heat Segmentation Heart Development Regulation Of Response To DNA Damage Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition
Tagcloud ?			achieve aida apl atra became chemotherapy consolidation converting courses cytogenetic fab gimema hematologic interpretation lap0493 m3 majority molecularly morphologic mths myelogenous persistence promyelocytic q12 q22 remission successive transcript validity
Tagcloud (Difference) ?			achieve aida apl atra became chemotherapy consolidation converting courses cytogenetic fab gimema hematologic interpretation lap0493 m3 majority molecularly morphologic mths myelogenous persistence promyelocytic q12 q22 remission successive transcript validity
Tagcloud (Intersection) ?