ANKS1B and HTR2A

  • Number of citations of the paper that reports this interaction (PubMedID 16537434)
  • 33
  • Data Source:
  • HPRD (two hybrid)

ANKS1B

HTR2A

Description ankyrin repeat and sterile alpha motif domain containing 1B 5-hydroxytryptamine receptor 2A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adult body size ( 32376654)
  • Alcohol dependence or heroin dependence or methamphetamine dependence ( 31462767)
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
  • Angiotensin-converting enzyme inhibitor intolerance ( 28030426)
  • Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Bipolar disorder ( 31043756)
  • Bipolar I disorder ( 31043756)
  • Body fat percentage ( 31752434)
  • Body mass index ( 20966902)
  • Body mass index and waist-hip ratio (pleiotropy) ( 29868124)
  • Body size at age 10 ( 32376654)
  • Electrodermal activity ( 25387706)
  • Hip circumference adjusted for BMI ( 34021172)
  • Left-handedness ( 32989287)
  • Metabolite levels (HVA/5-HIAA ratio) ( 23319000)
  • Obesity-related traits ( 23251661)
  • Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627)
  • Response to antipsychotic treatment ( 19721433)
  • Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)
  • Response to methotrexate in juvenile idiopathic arthritis ( 24709693)
  • Serum polyunsaturated fatty acid concentration x sex interaction in metabolic syndrome ( 31991592)
  • Waist circumference ( 20966902)
  • Cardiac hypertrophy ( 21348951)
  • Femur bone mineral density x serum urate levels interaction ( 34046847)
  • Parkinson disease and lewy body pathology ( 25663231)
  • Serum 25-Hydroxyvitamin D levels ( 29325163)
  • Sjögren's syndrome ( 28076899)
  • Subcutaneous adipose tissue ( 22589738)
Interacting Genes 14 interacting genes: APP CASS4 CREBBP EGFR ERBB2 ERBB4 HSF2BP HTR2A LRP1 LRP2 NCK2 RHOA RIN1 UBC 19 interacting genes: ANKS1B ARF1 ARF6 DLG1 DLG4 EIF3F GLUL GNA11 GNAI1 GNAQ JAK2 MAP1A MRPL28 NDUFB10 NME3 NTRK3 PON2 PPP5C RPS6KA3
Entrez ID 56899 3356
HPRD ID 07426 01638
Ensembl ID ENSG00000185046 ENSG00000102468
Uniprot IDs A0A804HKX1 B1VKB5 B7Z9I9 F8VR14 Q6V0K8 Q7Z6G8 A0A7P0PKG8 P28223
PDB IDs 2EAM 2KE7 2KIV 2M38 6A93 6A94 6WGT 6WH4 6WHA 7RAN 7VOD 7VOE 7WC4 7WC5 7WC6 7WC7 7WC8 7WC9 8JT8 8UWL 8V6U 8ZMG
Enriched GO Terms of Interacting Partners?
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