DUSP26 and HSF4

Number of citations of the paper that reports this interaction (PMID 16581800)
14

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)
HPRD (in vitro, two hybrid, in vivo)

		DUSP26	HSF4
Gene Name		dual specificity phosphatase 26 (putative)	heat shock transcription factor 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Golgi Apparatus Extracellular Vesicular Exosome	Nucleoplasm
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding P53 Binding Phosphoserine Phosphatase Activity Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Phosphatase Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Positive Regulation Of Cell Adhesion Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Peptidyl-serine Dephosphorylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Histone H3-K9 Demethylation Camera-type Eye Development Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Development Protein Homotrimerization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CALCOCO2 HSF4	10 interactors: CDK2AP2 DUSP26 MAPK1 MAPK14 MAPK3 MAPK8 NUDT21 SLC27A5 SMARCA4 ZBED8
Entrez ID		78986	3299
HPRD ID		14421	03896
Ensembl ID		ENSG00000133878	ENSG00000102878
Uniprot IDs		Q9BV47	Q9ULV5
PDB IDs		2E0T 4B04 4HRF
Enriched GO Terms of Interacting Partners?			Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway MAPK Cascade Regulation Of Golgi Inheritance Neurotrophin Signaling Pathway Regulation Of Innate Immune Response Caveolin-mediated Endocytosis Signal Transduction By Phosphorylation Response To Lipopolysaccharide Regulation Of Golgi Organization Response To Molecule Of Bacterial Origin Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification Regulation Of Early Endosome To Late Endosome Transport Cellular Response To Lipid Peptidyl-serine Phosphorylation Regulation Of Intracellular Transport Immune Response-regulating Signaling Pathway Response To Bacterium Activation Of MAPK Activity Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Factor Platelet Activation Growth Hormone Receptor Signaling Pathway Regulation Of MAPK Cascade Cellular Response To Growth Hormone Stimulus Positive Regulation Of Immune Response
Tagcloud ?		adopts allosteric alpha7 anticancer c152s canonical catalytic catalytically crossover dephosphorylating deviates dimer dusps exists exploited gaps governing helix hinge inactive insights loops noticeable phosphatases rational resolution surrounding swapped	a3 bf blinding cataract cataracts congenital constantly cryaa cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygc crygd crygs crystallin ftl gja1 gja3 gja8 lim2 maf mip pax6 pitx3 sp2 summarized
Tagcloud (Difference) ?		adopts allosteric alpha7 anticancer c152s canonical catalytic catalytically crossover dephosphorylating deviates dimer dusps exists exploited gaps governing helix hinge inactive insights loops noticeable phosphatases rational resolution surrounding swapped	a3 bf blinding cataract cataracts congenital constantly cryaa cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygc crygd crygs crystallin ftl gja1 gja3 gja8 lim2 maf mip pax6 pitx3 sp2 summarized
Tagcloud (Intersection) ?