BIRC7 and BOLA2B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BIRC7	BOLA2B
Description		baculoviral IAP repeat containing 7	bolA family member 2B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Centrosome Cytosol	Nucleus Cytoplasm Cytosol Iron-sulfur Cluster Assembly Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Cysteine-type Endopeptidase Inhibitor Activity Protein Binding Zinc Ion Binding Transferase Activity Enzyme Binding Peptidase Inhibitor Activity Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Iron-sulfur Cluster Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Lens Development In Camera-type Eye Apoptotic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Regulation Of Cell Population Proliferation Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Regulation Of Natural Killer Cell Apoptotic Process	Intracellular Iron Ion Homeostasis Iron-sulfur Cluster Assembly [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation
Pathways		Regulation of MITF-M-dependent genes involved in apoptosis	Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545)
Interacting Genes		37 interacting genes: AURKC BOLA1 BOLA2 BOLA2B CASP3 CASP7 CASP9 DDX6 DIABLO FAM124B GTF2A1 HTRA2 KANK2 LCOR LMO4 NTAQ1 PHF1 POLR1C PRR35 PSMB1 PTCD3 QARS1 SOX5 TEPSIN TLE5 TNPO2 TSGA10IP TTPA UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2I UBE2K USP2 VPS37C XAF1	32 interacting genes: ADAMTSL4 ANKRD55 BIRC2 BIRC7 C10orf55 C1orf94 CCDC138 CGGBP1 GLRX3 HDX ID3 IHO1 IL16 MBD3L1 MEOX2 MOBP NTAQ1 RAB4B RGS17 SLITRK5 TK1 TXNRD3 XIAP ZFP90 ZNF177 ZNF511 ZNF559-ZNF177 ZNF581 ZNF620 ZNF688 ZNF76 ZNF774
Entrez ID		79444	654483
HPRD ID		05761	19050
Ensembl ID		ENSG00000101197	ENSG00000169627
Uniprot IDs		Q96CA5	A0A499FJE1 Q9H3K6
PDB IDs		1OXN 1OXQ 1OY7 1TW6 2I3H 2I3I 3F7G 3F7H 3F7I 3GT9 3GTA 3UW5 4AUQ
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Proteolysis Protein Metabolic Process Macromolecule Catabolic Process Fibroblast Apoptotic Process Iron-sulfur Cluster Assembly Complex Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Neuron Apoptotic Process Nucleus Cysteine-type Endopeptidase Activity Proteolysis Involved In Protein Catabolic Process Macromolecule Metabolic Process Iron-sulfur Cluster Assembly Execution Phase Of Apoptosis Negative Regulation Of Macromolecule Biosynthetic Process Cellular Response To Staurosporine Cytosol Negative Regulation Of Biosynthetic Process Glial Cell Apoptotic Process Protein Maturation Post-translational Protein Modification Response To Interferon-beta Response To Anesthetic Negative Regulation Of Metabolic Process Cell Redox Homeostasis Protein Binding Negative Regulation Of Macromolecule Metabolic Process Leukocyte Apoptotic Process Negative Regulation Of Transcription By RNA Polymerase II Cysteine-type Peptidase Activity Response To Cobalt Ion Ubiquitin-protein Transferase Activity [2Fe-2S] Cluster Assembly CD40 Receptor Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Intracellular Iron Ion Homeostasis Protein Modification Process Positive Regulation Of Neuron Apoptotic Process Catabolic Process Apoptotic Process Intrinsic Apoptotic Signaling Pathway Histone Methyltransferase Binding Negative Regulation Of RNA Metabolic Process Protein Processing Protein Poly-ADP-ribosylation Programmed Cell Death	Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of RNA Metabolic Process Positive Regulation Of Protein Polyubiquitination Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Polyubiquitination Positive Regulation Of Post-translational Protein Modification Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Metal Ion Binding Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Cysteine-type Endopeptidase Inhibitor Activity Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Cellular Response To Leptomycin B Leptomycin B Binding Regulation Of Transcription By RNA Polymerase II Pigment Cell Development Protein-N-terminal Glutamine Amidohydrolase Activity Regulation Of Natural Killer Cell Apoptotic Process
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