CTNNBL1 and LBP

		CTNNBL1	LBP
Description		catenin beta like 1	lipopolysaccharide binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Centrosome Cytosol Membrane	Extracellular Region Extracellular Space Cell Surface Membrane Extracellular Exosome
	Molecular Function	Protein Binding Enzyme Binding	Lipopolysaccharide Binding Signaling Receptor Binding Protein Binding Lipid Binding Coreceptor Activity Lipoteichoic Acid Binding Lipopeptide Binding
	Biological Process	MRNA Splicing, Via Spliceosome Adaptive Immune Response Immune System Process MRNA Processing RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process	Leukocyte Chemotaxis Involved In Inflammatory Response Macrophage Activation Involved In Immune Response Immune System Process Cell Surface Pattern Recognition Receptor Signaling Pathway Lipid Transport Acute-phase Response Cellular Defense Response Opsonization Lipopolysaccharide Transport Neutrophil Chemotaxis Lipopolysaccharide-mediated Signaling Pathway Detection Of Molecule Of Bacterial Origin Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Defense Response To Bacterium Positive Regulation Of Macrophage Activation Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Lipoteichoic Acid Positive Regulation Of Neutrophil Chemotaxis
Pathways		mRNA Splicing - Major Pathway	Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14 Regulation of TLR by endogenous ligand Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Bone mineral density ( 17903296) California verbal learning test score ( 31596458) Falling risk ( 32999390) Fasting glucose ( 34074324)	Basophil percentage of white cells ( 32888494) Periodontitis (DPAL) ( 24024966)
Interacting Genes		26 interacting genes: BEX3 BUD31 CALCOCO1 CATIP CDCA7L CREBZF ERP29 HMGB1 HNRNPK IK LDOC1 LUC7L MAPK8IP2 MED4 MEOX2 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP SUMO2 U2SURP WBP11 ZCCHC10	18 interacting genes: APOA1 BAG6 BST1 C4BPA CAMP CBFA2T2 CD14 CFHR1 FTH1 HSPB1 PRDX4 PSMA3 PYCR3 RPS21 SETD1A SMAD3 TRA2A TSC22D4
Entrez ID		56259	3929
HPRD ID		10850	07175
Ensembl ID		ENSG00000132792	ENSG00000129988
Uniprot IDs		Q8WYA6	P18428 Q8TCF0
PDB IDs		4CB8 4CB9 4CBA 4HM9 4HNM 4MFU 4MFV 7ABI
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing RNA Metabolic Process RNA Processing MRNA Metabolic Process Spliceosomal Complex Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Speck Nucleoplasm Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Binding Positive Regulation Of Macromolecule Metabolic Process Macrophage Activation Involved In Immune Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Transcription Coactivator Activity Regulation Of Toll-like Receptor 4 Signaling Pathway Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Lipopolysaccharide Binding Protein Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Cellular Response To Stress Regulation Of MRNA Processing Ribonuclease E Activity Molecular Function Inhibitor Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Gene Expression	Regulation Of Interleukin-1 Production Regulation Of Interleukin-1 Beta Production Immune Response Immune System Process Positive Regulation Of Interleukin-1 Production Cytolysis By Host Of Symbiont Cells Positive Regulation Of Interleukin-1 Beta Production Extracellular Region Extracellular Exosome Regulation Of Immune System Process Humoral Immune Response Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Adrenal Gland Development Blood Microparticle Identical Protein Binding Regulation Of Immune Response Killing By Host Of Symbiont Cells Positive Regulation Of Immune System Process Positive Regulation Of Immune Response Response To Other Organism Response To Stress Activation Of Immune Response Lipopolysaccharide Binding Regulation Of Tumor Necrosis Factor Production Prostaglandin Production Involved In Inflammatory Response Biological Process Involved In Interaction With Symbiont Opsonin Receptor Activity Negative Regulation Of Protein Kinase C Signaling Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Humoral Immune Response Positive Regulation Of Stress Fiber Assembly Regulation Of Chemotaxis Tertiary Granule Lumen Regulation Of Cytokine Production Regulation Of Defense Response Protein Stabilization Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Cell-substrate Adhesion Complement Activation Positive Regulation Of Cytokine Production Cellular Response To Butyrate Positive Regulation Of Macrophage Inflammatory Protein 1 Alpha Production Positive Regulation Of Interleukin-8 Production Ferritin Complex Iron Ion Sequestering Activity Proteasome Complex
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