KIAA1217 and GCC1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		KIAA1217	GCC1
Gene Name		KIAA1217	GRIP and coiled-coil domain containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane
	Molecular Function	Molecular_function	Protein Binding
	Biological Process	Embryonic Skeletal System Development	Protein Targeting To Golgi
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193) Obesity (early onset extreme) ( 23563609)	Type 2 diabetes ( 22158537)
Protein-Protein Interactions		14 interactors: ABI2 EXOSC5 FHL2 FXR2 GCC1 GOLGA2 HSBP1 KRT15 NCK2 SIAH1 SORBS3 TEX11 TRAF1 VPS52	36 interactors: ABI2 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC85B CEP57 CEP70 COIL CPSF7 DNAJA3 FBF1 GLI1 GOLGA2 GTF2I IKBKG ITSN1 KIAA0753 KIAA1217 LZTS2 MCRS1 NAB2 NAV1 NECAB2 NINL OIP5 PAK7 SMARCD1 TFIP11 TRIM29 USHBP1 ZNF276
Entrez ID		56243	79571
HPRD ID		11132	07599
Ensembl ID		ENSG00000120549	ENSG00000179562
Uniprot IDs		Q5T5P2	A4D0Z4 Q96CN9
PDB IDs
Enriched GO Terms of Interacting Partners?			Apoptotic Process Programmed Cell Death Cell Death Death Organelle Organization Transcription, DNA-templated RNA Metabolic Process Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Intracellular Signal Transduction Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Developmental Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Toxin Metabolic Process Negative Regulation Of Cell Death Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase III Promoter Nitrogen Compound Metabolic Process G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Cell Communication Positive Regulation Vascular Endothelial Growth Factor Production Signal Transduction Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death System Development Multicellular Organismal Development Cellular Process NIK/NF-kappaB Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Biosynthetic Process Cell Cycle Positive Regulation Of Histone H4-K20 Methylation Spliceosomal Complex Disassembly Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination
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