PCDHB14 and PSTPIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PCDHB14	PSTPIP1
Description		protocadherin beta 14	proline-serine-threonine phosphatase interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Cell Adhesion Molecule Binding	Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Chemical Synaptic Transmission Nervous System Development Synapse Assembly Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules	Immune System Process Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response
Pathways			The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS			Hip circumference adjusted for BMI ( 34021172) Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		16 interacting genes: AKAP8L GOLGA6L9 HNRNPK HNRNPR KHDRBS3 KRT27 KRTAP6-3 MTUS2 PSTPIP1 PURB RBMX RBMY1A1 RBMY1F RBMY1J SRSF3 TRA2B	64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688
Entrez ID		56122	9051
HPRD ID		06958	05891
Ensembl ID		ENSG00000120327	ENSG00000140368
Uniprot IDs		Q9Y5E9	A0A0S2Z5P3 J3KPG6 O43586
PDB IDs			2DIL 7AAL 7AAM 7AAN
Enriched GO Terms of Interacting Partners?		MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing Regulation Of MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing RNA Processing MRNA Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Regulation Of MRNA Metabolic Process Positive Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Binding Positive Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Nucleoplasm RNA Splicing, Via Transesterification Reactions Protein Domain Specific Binding Regulation Of RNA Metabolic Process Catalytic Step 2 Spliceosome Pre-mRNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Splicing Positive Regulation Of Biosynthetic Process Ribonucleoprotein Complex Identical Protein Binding Nucleus Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-RNA Sequence-specific Adaptor Activity Cyclin K-CDK12 Complex Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Supraspliceosomal Complex Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Positive Regulation Of Low-density Lipoprotein Particle Clearance Purine-rich Negative Regulatory Element Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process	Actin Filament Polymerization Protein Polymerization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Actin Polymerization Or Depolymerization SH3 Domain Binding Negative Regulation Of Membrane Tubulation Protein Binding Regulation Of Plasma Membrane Organization MRNA Processing RNA Splicing MRNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Spliceosomal Tri-snRNP Complex Regulation Of Double-strand Break Repair Regulation Of DNA Repair Negative Regulation Of ERBB Signaling Pathway Lamellipodium Morphogenesis Negative Regulation Of Cellular Component Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Filament Organization Podosome Regulation Of Vitamin D Receptor Signaling Pathway Substrate-dependent Cell Migration, Cell Extension Spliceosomal Complex Actin Cytoskeleton Ruffle SCAR Complex
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