PCDHB14 and PURB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PCDHB14	PURB
Description		protocadherin beta 14	purine rich element binding protein B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synapse	Nucleus Nucleoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Cell Adhesion Molecule Binding	MRNA Regulatory Element Binding Translation Repressor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding DNA-binding Transcription Factor Activity RNA Binding MRNA Binding Protein Binding Purine-rich Negative Regulatory Element Binding SMAD Binding DNA-binding Transcription Factor Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Chemical Synaptic Transmission Nervous System Development Synapse Assembly Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Translation Regulation Of Myeloid Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Platelet count ( 27863252)
Interacting Genes		16 interacting genes: AKAP8L GOLGA6L9 HNRNPK HNRNPR KHDRBS3 KRT27 KRTAP6-3 MTUS2 PSTPIP1 PURB RBMX RBMY1A1 RBMY1F RBMY1J SRSF3 TRA2B	25 interacting genes: AP1M1 CEBPA CSNK2A1 IL7R LNX1 MBD2 MIR128-1 MIR128-2 MIR25 MIR29C MIR31 MIR34B MIR363 MIR7-1 MIR7-3 MIR9-2 MIRLET7A3 MIRLET7G MIRLET7I NABP1 NXF1 PCDHB14 PURA RBFOX2 ZNF497
Entrez ID		56122	5814
HPRD ID		06958	12325
Ensembl ID		ENSG00000120327	ENSG00000146676
Uniprot IDs		Q9Y5E9	Q96QR8
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing Regulation Of MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing RNA Processing MRNA Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Regulation Of MRNA Metabolic Process Positive Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Binding Positive Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Nucleoplasm RNA Splicing, Via Transesterification Reactions Protein Domain Specific Binding Regulation Of RNA Metabolic Process Catalytic Step 2 Spliceosome Pre-mRNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Splicing Positive Regulation Of Biosynthetic Process Ribonucleoprotein Complex Identical Protein Binding Nucleus Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-RNA Sequence-specific Adaptor Activity Cyclin K-CDK12 Complex Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Supraspliceosomal Complex Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Positive Regulation Of Low-density Lipoprotein Particle Clearance Purine-rich Negative Regulatory Element Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Translation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Regulation Of Macromolecule Metabolic Process Regulation Of Translation Regulation Of Metabolic Process Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Negative Regulation Of Protein Metabolic Process Regulation Of Cardiac Muscle Hypertrophy In Response To Stress RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Vasculature Development Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of Angiogenesis Negative Regulation Of Cell Motility Negative Regulation Of Cell Migration Negative Regulation Of Lipoprotein Transport MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Interleukin-34 Production Negative Regulation Of Cell Cycle Negative Regulation Of Locomotion Regulation Of Cell Population Proliferation
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