ZKSCAN7 and ZNF446

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		ZKSCAN7	ZNF446
Description		zinc finger with KRAB and SCAN domains 7	zinc finger protein 446
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Extracellular Space Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Generic Transcription Pathway	Generic Transcription Pathway
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661) Uric acid clearance ( 28095793)
Interacting Genes		14 interacting genes: CRK NFIC PGBD1 PLCG2 RHOU SCAND1 TCEANC ZKSCAN4 ZNF446 ZSCAN12 ZSCAN21 ZSCAN22 ZSCAN23 ZSCAN32	54 interacting genes: ACTN2 ANKRD1 CCNK COPS2 CYSRT1 DGCR6 DGCR6L EHMT2 EVI5 FHL5 FRMD8 FRS3 GOLGA6L9 INCA1 KIFC3 KRT31 KRT34 KRT35 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-3 KRTAP3-1 LNX1 LZTS2 MAGOHB MDFI NBPF19 NOTCH2NLA PIN1 REL SCAND1 SIVA1 SUFU TAX1BP1 TRIM27 UBE2I UBE3A ZKSCAN7 ZNF165 ZNF18 ZNF232 ZNF24 ZNF263 ZNF496 ZSCAN12 ZSCAN16 ZSCAN18 ZSCAN21 ZSCAN22 ZSCAN29 ZSCAN30 ZSCAN32 ZSCAN9
Entrez ID		55888	55663
HPRD ID		15744	07934
Ensembl ID		ENSG00000196345	ENSG00000083838
Uniprot IDs		A7MAY2 C9J6L6 Q0VAP0 Q9P0L1	Q9NWS9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Response To Yeast DNA Binding Zinc Ion Binding Protein Tyrosine Kinase Binding Phosphotyrosine Residue Binding Sequence-specific Double-stranded DNA Binding Response To Fungus Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Scaffold Protein Binding Response To Cholecystokinin Nucleus Cerebellar Neuron Development Inositol Trisphosphate Biosynthetic Process Establishment Of Cell Polarity	Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Keratin Filament Regulation Of RNA Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Regulation Of Gene Expression Structural Constituent Of Skin Epidermis Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process DNA Binding Nucleus Regulation Of Metabolic Process Intermediate Filament Organization Metal Ion Binding Postsynaptic Cytosol Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Molecule Activity Protein Binding Sequence-specific Double-stranded DNA Binding Titin Binding
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