LMO3 and KRT38

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LMO3	KRT38
Description		LIM domain only 3	keratin 38
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway	Morphogenesis Of An Epithelium Epithelial Cell Differentiation Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Chronotype ( 30696823) Household income (MTAG) ( 31844048) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Smoking initiation ( 33082346) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		124 interacting genes: ABI2 ACTMAP AIMP2 AMIGO1 AMOTL2 AVPI1 BANP BCAS2 BEND5 BEND7 BHLHE40 BLZF1 CARD9 CARF CBY2 CCDC33 CCDC85B CCSER1 CDYL2 CEP170P1 CEP57 CEP57L1 CYSRT1 DCDC2 DVL2 DYRK1A FAM131C FBLIM1 FOS GABPB1 GMEB2 GOLGA2 GOLGA6L9 GPATCH2L HMBOX1 HNRNPC HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IL16 INCA1 ITSN1 KANK2 KCTD1 KIF2A KRABD4 KRT31 KRT38 KXD1 LDB1 LDB2 LIMS1 LNPK LPXN LZTS1 LZTS2 MAD1L1 MALSU1 MBD3 MBD3L1 MBIP MDFI MEIS3 MID2 MTUS2 MYOG MYOZ3 NBPF22P NDOR1 NFKBID NHLH2 NIF3L1 NTAQ1 NUTM1 PELO PHC2 PICK1 PNMA1 POU6F2 PPP1R13B PXN QRICH1 RALYL RCN1 RFC5 RFX6 RORA SAMD3 SH2B2 SHISA6 SLAIN1 SP4 TAX1BP1 TCP10L TEPSIN THAP1 TMEM121 TRAPPC2L TRIB3 TRIM23 TRIM54 TUFT1 USP54 VBP1 VMAC VPS28 WASHC1 WWOX ZBTB43 ZBTB8A ZBTB8B ZIM3 ZNF143 ZNF526 ZNF587 ZNF620 ZNF641 ZNF69 ZNF84 ZRANB1 ZSCAN9	72 interacting genes: - ABI3 AMOTL2 ANKRD36BP1 BEX2 BRME1 C1orf216 CCDC120 CCDC146 CD300A CEP57L1 DMRT3 DTNB FAM110A FAM90A1 GLRX3 GNG10 GNG13 HAUS1 HDAC4 HGS HMG20B HOXA1 HSF4 KDM1A KIFC3 KLHL38 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6B KRT6C KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT86 LHX4 LMO3 LMO4 MAGEB4 MAPKBP1 PIK3R2 PIN1 POU4F2 PSMA1 PSMC5 PTGER3 RHPN1-AS1 SCNM1 SMARCD1 TBC1D21 TRIML2 TXLNA TXLNB TXNDC5 USHBP1 UTP23 ZFYVE21 ZNF20 ZNF417 ZNF587
Entrez ID		55885	8687
HPRD ID		11832	05176
Ensembl ID		ENSG00000048540	ENSG00000171360
Uniprot IDs		Q8TAP4 Q9NYC6	O76015
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Microtubule Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding	Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Organization Keratin Filament Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Supramolecular Fiber Organization Organelle Organization Protein Binding Extracellular Exosome Intermediate Filament Cytoskeleton Epidermis Development
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