LMO3 and ZNF69

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LMO3	ZNF69
Description		LIM domain only 3	zinc finger protein 69
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Chronotype ( 30696823) Household income (MTAG) ( 31844048) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Smoking initiation ( 33082346) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)	Mean corpuscular hemoglobin ( 32888494)
Interacting Genes		124 interacting genes: ABI2 ACTMAP AIMP2 AMIGO1 AMOTL2 AVPI1 BANP BCAS2 BEND5 BEND7 BHLHE40 BLZF1 CARD9 CARF CBY2 CCDC33 CCDC85B CCSER1 CDYL2 CEP170P1 CEP57 CEP57L1 CYSRT1 DCDC2 DVL2 DYRK1A FAM131C FBLIM1 FOS GABPB1 GMEB2 GOLGA2 GOLGA6L9 GPATCH2L HMBOX1 HNRNPC HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IL16 INCA1 ITSN1 KANK2 KCTD1 KIF2A KRABD4 KRT31 KRT38 KXD1 LDB1 LDB2 LIMS1 LNPK LPXN LZTS1 LZTS2 MAD1L1 MALSU1 MBD3 MBD3L1 MBIP MDFI MEIS3 MID2 MTUS2 MYOG MYOZ3 NBPF22P NDOR1 NFKBID NHLH2 NIF3L1 NTAQ1 NUTM1 PELO PHC2 PICK1 PNMA1 POU6F2 PPP1R13B PXN QRICH1 RALYL RCN1 RFC5 RFX6 RORA SAMD3 SH2B2 SHISA6 SLAIN1 SP4 TAX1BP1 TCP10L TEPSIN THAP1 TMEM121 TRAPPC2L TRIB3 TRIM23 TRIM54 TUFT1 USP54 VBP1 VMAC VPS28 WASHC1 WWOX ZBTB43 ZBTB8A ZBTB8B ZIM3 ZNF143 ZNF526 ZNF587 ZNF620 ZNF641 ZNF69 ZNF84 ZRANB1 ZSCAN9	12 interacting genes: CFTR FAM124B FRS3 GTPBP3 KATNAL1 KRT31 LMNA LMO3 MEOX2 P4HB SMARCD1 ZNF417
Entrez ID		55885	7620
HPRD ID		11832	11836
Ensembl ID		ENSG00000048540	ENSG00000198429
Uniprot IDs		Q8TAP4 Q9NYC6	Q9UC07
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Microtubule Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding	NBAF Complex RSC-type Complex NpBAF Complex GBAF Complex Nuclear Matrix Nucleosome Disassembly Protein-DNA Complex Disassembly Isomerase Activity Regulation Of Nucleotide-excision Repair SWI/SNF Complex Regulation Of G0 To G1 Transition Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Regulation Of Chromosome Organization Positive Regulation Of Gene Expression, Epigenetic Positive Regulation Of Stem Cell Population Maintenance Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Myoblast Differentiation Positive Regulation Of Anion Channel Activity DNA Double-strand Break Attachment To Nuclear Envelope Epigenetic Regulation Of Gene Expression Structural Constituent Of Nuclear Lamina Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Procollagen-proline 4-dioxygenase Complex Regulation Of Stem Cell Population Maintenance Transcription Coactivator Activity Regulation Of Myoblast Differentiation Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway TRNA 5-taurinomethyluridine Synthase Activity Mitochondrial TRNA Wobble Uridine Modification Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition ATP Hydrolysis Activity Positive Regulation Of Double-strand Break Repair Structural Constituent Of Cytoskeleton Positive Regulation Of Enamel Mineralization Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Peptidyl-proline Hydroxylation Regulation Of Sister Chromatid Segregation Regulation Of Glucose Mediated Signaling Pathway Transepithelial Water Transport Lamin Filament Nuclear Pore Localization Somite Specification Procollagen-proline 4-dioxygenase Activity Nucleosome Array Spacer Activity Positive Regulation Of T Cell Differentiation
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