LMO3 and LDB1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		LMO3	LDB1
Gene Name		LIM domain only 3 (rhombotin-like 2)	LIM domain binding 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Nuclear Chromatin Nucleus Transcription Factor Complex Protein Complex
	Molecular Function	Zinc Ion Binding	RNA Polymerase II Activating Transcription Factor Binding Enhancer Sequence-specific DNA Binding Chromatin Binding Transcription Corepressor Activity Enzyme Binding LIM Domain Binding Protein Homodimerization Activity Protein Self-association
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glucocorticoid Receptor Signaling Pathway	Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Gastrulation With Mouth Forming Second Hair Follicle Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Multicellular Organismal Development Anterior/posterior Axis Specification Epithelial Structure Maintenance Wnt Signaling Pathway Cerebellar Purkinje Cell Differentiation Cellular Component Assembly Neuron Differentiation Regulation Of DNA-templated Transcription, Elongation Somatic Stem Cell Maintenance Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Cell Adhesion Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hemoglobin Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: AIMP2 BANP CARF CCDC33 CCDC85B CEP170P1 CEP57L1 FAM131C FBLIM1 FOS GABPB1 HNRNPC HNRNPM IKZF1 KCTD1 KXD1 LDB1 LDB2 MBIP MDFI NBPF22P NHLH2 NUTM1 PHC2 RALYL RFX6 RORA SAMD3 SP4 SPERT TAX1BP1 ZBTB43 ZBTB8A	26 interactors: ATXN1 CTDSP1 ESR1 IRAK3 ISL1 LHX2 LHX3 LHX6 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP
Entrez ID		55885	8861
HPRD ID		11832	09144
Ensembl ID		ENSG00000048540	ENSG00000198728
Uniprot IDs		Q8TAP4 Q9NYC6	Q86U70
PDB IDs			2XJY 2XJZ 2YPA
Enriched GO Terms of Interacting Partners?		RNA Metabolic Process Gene Expression Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Epithelial Structure Maintenance Transcription From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Metabolic Process Chromatin Modification Cerebellar Cortex Formation Cell Differentiation In Hindbrain Cerebellar Purkinje Cell Layer Development Cellular Metabolic Process Chromatin Organization Regulation Of Myeloid Cell Differentiation Cerebellar Cortex Morphogenesis Cellular Response To Calcium Ion Histone H3 Acetylation Positive Regulation Of Neutrophil Differentiation Histone H3-K4 Acetylation Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Pancreatic Epsilon Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Calcium Ion Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Pancreatic D Cell Differentiation Positive Regulation Of Myeloid Leukocyte Differentiation	Gene Expression Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Central Nervous System Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Central Nervous System Development Cellular Metabolic Process Brain Development Head Development Developmental Process Organ Development Anatomical Structure Development Forebrain Development Tube Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Specification Process Cell Differentiation Negative Regulation Of Signal Transduction Multicellular Organismal Development Neuron Differentiation Anatomical Structure Morphogenesis System Development Spinal Cord Motor Neuron Differentiation Generation Of Neurons Negative Regulation Of Signaling Transcription From RNA Polymerase II Promoter Neurogenesis
Tagcloud ?		aggressive aggressiveness atypical benign biosignatures clinically constitute decisions demand forty fourteen histologically igf1r meningioma meningiomas metabolic mostly nmr oligonucleotide otherwise predominant proceeds profiles recur recurrence relevance subgroup subgroups turnover	assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose
Tagcloud (Difference) ?		aggressive aggressiveness atypical benign biosignatures clinically constitute decisions demand forty fourteen histologically igf1r meningioma meningiomas metabolic mostly nmr oligonucleotide otherwise predominant proceeds profiles recur recurrence relevance subgroup subgroups turnover	assemble bhlh compatible consensus e12 erythroid erythroleukemia erythropoiesis exist forced g1er hemopoietic immature lbd1 lim lmo2 maintain maturation mediate multiprotein normally oncoprotein others precursors presumed primarily proerythroblast scl whose
Tagcloud (Intersection) ?