CENPJ and ATN1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CENPJ	ATN1
Gene Name		centromere protein J	atrophin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Centriole Cytosol Microtubule Gamma-tubulin Small Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Tubulin Binding Protein Kinase Binding Protein Domain Specific Binding	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Microtubule Nucleation Centriole Replication Regulation Of Centriole Replication Microtubule Polymerization Cell Division	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ATN1 CIC CREBBP EPB41 GFI1B LAG3 LYST RELA STAT5A STAT5B TUBG1 YWHAG YWHAZ	93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		55835	1822
HPRD ID		09876	06311
Ensembl ID		ENSG00000151849	ENSG00000111676
Uniprot IDs		A8K8P1 Q9HC77	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Interleukin-2 Biosynthetic Process Positive Regulation Of Natural Killer Cell Activation Regulation Of Cytokine Biosynthetic Process Development Of Secondary Male Sexual Characteristics Creatinine Metabolic Process Positive Regulation Of Innate Immune Response Isoleucine Metabolic Process Allantoin Metabolic Process Taurine Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Cytokine Production Negative Regulation Of Erythrocyte Differentiation Prolactin Signaling Pathway Regulation Of Innate Immune Response Positive Regulation Of Gamma-delta T Cell Activation Development Of Secondary Female Sexual Characteristics Valine Metabolic Process Creatine Metabolic Process Positive Regulation Of Natural Killer Cell Differentiation Succinate Metabolic Process Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics Luteinization Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Interleukin-2 Biosynthetic Process Cellular Response To Peptide Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of B Cell Differentiation 2-oxoglutarate Metabolic Process Peyer's Patch Development Positive Regulation Of Cytokine Production Oxaloacetate Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Lymphocyte Activation Natural Killer Cell Differentiation Immune System Process Positive Regulation Of Activated T Cell Proliferation JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Immune System Process	Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development
Tagcloud ?		acentriolar assembled biogenesis bipolar centriole centrioles centrosomes cilia cpap dividing embryos hedgehog interphase microtubule microtubules midgestation mutants organize organizing poles prolonging prometaphase rescued sas4 segregation spindle spindles survive undescribed	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		acentriolar assembled biogenesis bipolar centriole centrioles centrosomes cilia cpap dividing embryos hedgehog interphase microtubule microtubules midgestation mutants organize organizing poles prolonging prometaphase sas4 segregation spindle spindles survive undescribed	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression seq surprisingly tranylcypromine
Tagcloud (Intersection) ?		rescued