ADAP2 and NCL

Number of citations of the paper that reports this interaction (PMID 18298663)
4

Data Source:
BioGRID (pull down)

		ADAP2	NCL
Gene Name		ArfGAP with dual PH domains 2	nucleolin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Envelope Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cell Cortex Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding ARF GTPase Activator Activity Zinc Ion Binding Protein Binding, Bridging Phosphatidylinositol-3,4-bisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding	Nucleotide Binding RNA Binding Protein Binding Protein C-terminus Binding Telomeric DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Heart Development Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity	Angiogenesis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter
Pathways
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 23728934) Eating disorders (purging via substances) ( 23568457)
Protein-Protein Interactions		8 interactors: APP EEF1G IKBKG NCL NEDD4L PRNP RANBP9 SNCA	48 interactors: ADAP1 ADAP2 CD3E CD3EAP CDK1 CDKN2A CSNK2A1 CSNK2A2 ERG ETS1 FMR1 GRB2 GZF1 GZMA H2AFX HIST1H1C HIST2H2AC HIST2H2BE HIST3H3 HMGA1 IL7R MDC1 MDK MDM2 MYB MYBL1 NBN NDRG1 NPM1 NR3C1 PARP1 PPARGC1A PPM1D PRKCZ PTGS1 S100A11 SREK1 SSB STAU1 TERF2 TERT TOP1 TP53 VHL XRCC6 YWHAQ ZFP36 ZNF689
Entrez ID		55803	4691
HPRD ID		16357	01245
Ensembl ID		ENSG00000184060
Uniprot IDs		Q2V6Q1 Q9NPF8	B3KM80 P19338 Q9BQ02
PDB IDs			2FC8 2FC9 2KRR
Enriched GO Terms of Interacting Partners?		Cellular Response To Copper Ion Response To External Stimulus Cellular Copper Ion Homeostasis Response To Copper Ion Copper Ion Homeostasis Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Metal Ion Regulation Of Potassium Ion Transport Axon Guidance Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Cellular Metal Ion Homeostasis Response To Oxidative Stress Regulation Of Protein Metabolic Process Cellular Cation Homeostasis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Negative Regulation Of Signaling Single-organism Behavior Cellular Ion Homeostasis Metal Ion Homeostasis Response To Inorganic Substance Positive Regulation Of Protein Metabolic Process Negative Regulation Of Ion Transport Regulation Of Phosphorylation Positive Regulation Of Endocytosis Axonogenesis Cellular Chemical Homeostasis Adult Locomotory Behavior Homeostatic Process Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Ion Homeostasis Regulation Of Transcription, DNA-templated Axon Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Morphogenesis Involved In Neuron Differentiation Behavior Cellular Response To Metal Ion Chemotaxis Regulation Of Phosphorus Metabolic Process Regulation Of RNA Metabolic Process	Chromosome Organization DNA Conformation Change Positive Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Aging Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cell Cycle Chromatin Organization Response To Stimulus Nucleobase-containing Compound Metabolic Process Cellular Response To Stress DNA Packaging Cellular Response To Stimulus Developmental Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To DNA Damage Stimulus Regulation Of Gene Expression Regulation Of Apoptotic Process Chromatin Assembly Telomere Maintenance Cellular Nitrogen Compound Metabolic Process Cell Cycle Checkpoint Regulation Of Cell Death Chromatin Assembly Or Disassembly Response To Stress Mitotic Cell Cycle Checkpoint Regulation Of Cell Proliferation DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cell Aging Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Aging Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Regulation Of Cellular Process RNA Biosynthetic Process Cellular Senescence Double-strand Break Repair Protein Complex Assembly DNA Damage Checkpoint Cell Cycle Process Regulation Of RNA Metabolic Process Mitotic Cell Cycle Process
Tagcloud ?			affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Difference) ?			affinity capping corresponding deletion eif end eucaryotic fold free germ hairpin initiation interference leader loop mrna noncoding ovalbumin rabbit rate recognition restored reticulocyte secondary sequence structure systems translation wheat
Tagcloud (Intersection) ?