ADAP2 and RANBP9

Number of citations of the paper that reports this interaction (PMID 18298663)
4

Data Source:
BioGRID (pull down)

		ADAP2	RANBP9
Gene Name		ArfGAP with dual PH domains 2	RAN binding protein 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrial Envelope Plasma Membrane	Nucleus Cytosol Microtubule Associated Complex
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-3,4,5-trisphosphate Binding ARF GTPase Activator Activity Zinc Ion Binding Protein Binding, Bridging Phosphatidylinositol-3,4-bisphosphate Binding Inositol 1,3,4,5 Tetrakisphosphate Binding	Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Heart Development Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity	Protein Complex Assembly Microtubule Nucleation Axon Guidance
Pathways			Axon guidance L1CAM interactions
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		8 interactors: APP EEF1G IKBKG NCL NEDD4L PRNP RANBP9 SNCA	51 interactors: ADAP1 ADAP2 APC AR AXL BACE1 BRCA1 CACNA1G CALB1 CBS CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 OPRM1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1
Entrez ID		55803	10048
HPRD ID		16357	04835
Ensembl ID		ENSG00000184060	ENSG00000010017
Uniprot IDs		Q2V6Q1 Q9NPF8	Q96S59
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Copper Ion Response To External Stimulus Cellular Copper Ion Homeostasis Response To Copper Ion Copper Ion Homeostasis Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Transporter Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Metal Ion Regulation Of Potassium Ion Transport Axon Guidance Regulation Of Protein Phosphorylation Negative Regulation Of Signal Transduction Cellular Metal Ion Homeostasis Response To Oxidative Stress Regulation Of Protein Metabolic Process Cellular Cation Homeostasis Negative Regulation Of Thrombin Receptor Signaling Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Negative Regulation Of Signaling Single-organism Behavior Cellular Ion Homeostasis Metal Ion Homeostasis Response To Inorganic Substance Positive Regulation Of Protein Metabolic Process Negative Regulation Of Ion Transport Regulation Of Phosphorylation Positive Regulation Of Endocytosis Axonogenesis Cellular Chemical Homeostasis Adult Locomotory Behavior Homeostatic Process Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Synaptic Growth At Neuromuscular Junction Positive Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Transcription Of Nuclear Large RRNA Transcript From RNA Polymerase I Promoter Ion Homeostasis Regulation Of Transcription, DNA-templated Axon Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cell Morphogenesis Involved In Neuron Differentiation Behavior Cellular Response To Metal Ion Chemotaxis Regulation Of Phosphorus Metabolic Process Regulation Of RNA Metabolic Process	Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Organ Development Response To Organic Substance Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Organic Substance Signal Transduction Cellular Response To Organic Cyclic Compound Signaling DNA-templated Transcription, Initiation Cellular Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Response To Stimulus Response To Organic Cyclic Compound Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Tissue Development Response To Lipid Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Response To Growth Factor Epithelium Development Wound Healing Negative Regulation Of Signal Transduction Regulation Of Cell Proliferation Response To Hormone Reproductive Process Regulation Of Intracellular Signal Transduction Apoptotic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cell Activation Negative Regulation Of Signaling DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Tagcloud ?			accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Difference) ?			accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Intersection) ?