SH3BP5 and DST

Number of citations of the paper that reports this interaction (PubMedID 17043677)
0

Data Source:
BioGRID (two hybrid)

		SH3BP5	DST
Description		SH3 domain binding protein 5	dystonin
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Membrane Nuclear Body Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle	Stress Fiber Basement Membrane Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Microtubule Intermediate Filament Plasma Membrane Focal Adhesion Cell Cortex Basal Plasma Membrane Actin Cytoskeleton Microtubule Cytoskeleton Membrane Z Disc Hemidesmosome Axon Cell Leading Edge Cytoplasmic Vesicle H Zone Microtubule Plus-end Cell Projection Intermediate Filament Cytoskeleton Anchoring Junction Cell Periphery Polymeric Cytoskeletal Fiber Axon Cytoplasm
	Molecular Function	Protein Kinase Inhibitor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding SH3 Domain Binding	Actin Binding Integrin Binding Structural Molecule Activity Calcium Ion Binding Protein Binding Microtubule Binding Protein Homodimerization Activity Metal Ion Binding Microtubule Plus-end Binding
	Biological Process	Signal Transduction Intracellular Signal Transduction	Microtubule Cytoskeleton Organization Cytoskeleton Organization Cell Adhesion Integrin-mediated Signaling Pathway Retrograde Axonal Transport Response To Wounding Maintenance Of Cell Polarity Hemidesmosome Assembly Wound Healing Intermediate Filament Cytoskeleton Organization Cell Motility
Pathways			Type I hemidesmosome assembly RHOU GTPase cycle RHOV GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439) Heschl's gyrus morphology ( 25130324) Prudent dietary pattern ( 28644415)	Alzheimer disease and age of onset ( 26830138) Appendicular lean mass ( 33097823) Attention function in attention deficit hyperactive disorder ( 26174813) Cerebrospinal fluid clusterin levels ( 26545630) Daytime sleep phenotypes ( 27126917) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Mean spheric corpuscular volume ( 32888494) Menarche (age at onset) ( 25231870) Red blood cell count ( 32888494) Small cell lung carcinoma ( 28604730)
Interacting Genes		16 interacting genes: APP BTK CDC5L DISC1 DST EXOC1 IFT20 MAPK10 MAPK12 MAPK8 MAPK9 NAP1L2 SOS1 SPTBN1 SYNE1 TTC3	50 interacting genes: ABI1 ANKRD1 APC C1QTNF9 CALM1 CDC5L CELSR3 CEP63 CLIP4 COL17A1 DCTN1 DISC1 DSCAM DSCR9 DTNBP1 ECPAS EIF4ENIF1 ERBB2 ERBIN EXOC1 FTCD HUNK ITGB4 ITSN1 ITSN2 KIAA1549 KRT14 KRT5 LINC01554 MAPK6 MORC3 MTNR1B MYBPC2 NFYC NRIP1 PAK2 PCNT PRKAB2 PRKD2 PTGER4 RBM11 RSPH1 SH3BP5 SMAD9 SNAPIN TNIK TRAF3IP1 TTC3 TULP3 USP7
Entrez ID		9467	667
HPRD ID		12030	00222
Ensembl ID		ENSG00000131370	ENSG00000151914
Uniprot IDs		O60239	A0A7P0T890 B4DGY0 B4DSS9 E9PHM6 F6QMI7 F8W9J4 Q03001 Q6P0N6
PDB IDs		4H3B 6DJL 6IXE 6IXF 6IXG 6IXV	3GJO 7OLG
Enriched GO Terms of Interacting Partners?		Fc-epsilon Receptor Signaling Pathway JUN Kinase Activity MAP Kinase Activity Fc Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Intracellular Signaling Cassette Intracellular Signal Transduction Cytoplasm Cell Surface Receptor Signaling Pathway Peptidase Activator Activity Immune Response-regulating Signaling Pathway JNK Cascade Cellular Senescence MAPK Cascade Protein Kinase Activity Positive Regulation Of Cell Differentiation Regulation Of Immune Response Cellular Response To Reactive Oxygen Species Regulation Of Circadian Rhythm Response To Light Stimulus Kinase Activity Protein Serine/threonine Kinase Binding Regulation Of Cell Differentiation Signal Transduction Protein Phosphorylation Protein Serine Kinase Activity Positive Regulation Of Cellular Component Organization Phosphorylation Axon Cytosol Response To Reactive Oxygen Species Positive Regulation Of NLRP3 Inflammasome Complex Assembly Protein Serine/threonine Kinase Activity Transport Along Microtubule Regulation Of Protein-containing Complex Assembly Response To Radiation Positive Regulation Of Proteolysis Amyloid-beta Complex Growth Cone Lamellipodium Cytoskeleton-dependent Intracellular Transport Regulation Of Response To Calcium Ion Response To Stress Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Developmental Process Regulation Of B Cell Cytokine Production Monocyte Proliferation Positive Regulation Of Interleukin-17A Production Cellular Response To Oxidative Stress Positive Regulation Of Protein-containing Complex Assembly	Signal Transduction Hemidesmosome Cytoskeleton Organization Intracellular Signal Transduction Clathrin-dependent Synaptic Vesicle Endocytosis Regulation Of Dendritic Spine Development Plasma Membrane Bounded Cell Projection Organization Cell Projection Organization Centrosome Developmental Process Cytosol Hemidesmosome Assembly Cytoplasm Vesicle-mediated Transport In Synapse Organelle Organization Molecular Adaptor Activity Anatomical Structure Morphogenesis Cytoskeleton Regulation Of Neuron Projection Development Ciliary Base Presynaptic Endocytosis Cellular Component Assembly Cell Junction Organization Dendrite Morphogenesis Cell Surface Receptor Signaling Pathway Protein Binding Microtubule-based Process Protein Phosphorylation Plasma Membrane Bounded Cell Projection Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Titin Binding Nucleoplasm Cell Junction Assembly Regulation Of Cell Projection Organization Cell Projection Assembly Cell Leading Edge Cilium Assembly Axonal Transport Organelle Assembly Neuron Cellular Homeostasis Dendritic Spine Development Neuron Projection Morphogenesis Phosphorylation Basal Plasma Membrane Protein Tyrosine Kinase Activator Activity Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Anterograde Synaptic Vesicle Transport BLOC-1 Complex Positive Regulation Of Cell Growth
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