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SH3BP5
Gene Name
SH3-domain binding protein 5 (BTK-associated)
Image
Gene Ontology Annotations
Cellular Component
Cytoplasm
Mitochondrion
Molecular Function
Protein Kinase Inhibitor Activity
Protein Binding
SH3 Domain Binding
Biological Process
Negative Regulation Of Protein Kinase Activity
Signal Transduction
Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
Alcohol and nictotine co-dependence (
22488850
)
Alcohol dependence (
21956439
)
Protein-protein Interactions
14 interactors:
APP
BTK
CDC5L
DISC1
DST
EXOC1
MAPK10
MAPK12
MAPK8
MAPK9
SOS1
SPTBN1
SYNE1
TNKS
Entrez ID
9467
HPRD ID
12030
Ensembl ID
ENSG00000131370
Uniprot IDs
O60239
PDB IDs
4H3B
Enriched GO Terms of Interacting Partners
?
JUN Phosphorylation
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Cell Surface Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Protein Phosphorylation
Fc Receptor Signaling Pathway
Toll-like Receptor Signaling Pathway
Signal Transduction
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of Innate Immune Response
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Signaling
Cell Communication
Phosphorylation
Intracellular Signal Transduction
Positive Regulation Of Innate Immune Response
Innate Immune Response
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Immune Response-regulating Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MAPK Cascade
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Innate Immune Response
Cellular Response To Stimulus
Signal Transduction By Phosphorylation
JNK Cascade
Cellular Localization
Positive Regulation Of Proteolysis
Regulation Of Circadian Rhythm
Response To Stress
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Response To Light Stimulus
Apoptotic Signaling Pathway
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Peptidyl-serine Phosphorylation
Positive Regulation Of Signal Transduction
Immune Response
Defense Response
Phosphate-containing Compound Metabolic Process
Positive Regulation Of Peptidase Activity
Regulation Of Immune Response
Tagcloud
?
activator
apollon
bioactive
bruce
context
deaths
effector
familial
heterotrimeric
hthnr
humanin
inhibits
jaks
janus
linked
london
member
neuronal
occurs
precursor
sole
stat3
transducer
unusual
upregulated
v642i
variety
via