TRAF3IP1 and DMD

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		TRAF3IP1	DMD
Gene Name		TNF receptor-associated factor 3 interacting protein 1	dystrophin
Image
Gene Ontology Annotations	Cellular Component	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Primary Cilium Ciliary Tip	Nucleus Cytosol Cytoskeleton Plasma Membrane Cell Surface Actin Cytoskeleton Dystrophin-associated Glycoprotein Complex Syntrophin Complex Lateral Plasma Membrane Cell Junction Filopodium Filopodium Membrane Sarcolemma Costamere Protein Complex Membrane Raft Postsynaptic Membrane
	Molecular Function	Protein Binding Microtubule Binding	Dystroglycan Binding Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Zinc Ion Binding Structural Constituent Of Muscle Myosin Binding Vinculin Binding Nitric-oxide Synthase Binding
	Biological Process	Organelle Organization Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Post-anal Tail Morphogenesis Intraciliary Transport Cilium Assembly Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning	Regulation Of Heart Rate Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Neuron Projection Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Skeletal Muscle Contraction Muscle Filament Sliding Extracellular Matrix Organization Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Protein Localization Peptide Biosynthetic Process Cellular Protein Complex Assembly Motile Cilium Assembly Positive Regulation Of Neuron Differentiation Cardiac Muscle Contraction Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Cell Action Potential Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Voltage-gated Calcium Channel Activity Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport	Striated Muscle Contraction Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS		Iris characteristics ( 21835309)	Response to antidepressant treatment ( 22041458)
Protein-Protein Interactions		27 interactors: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 WAC	27 interactors: ACTA1 ACTC1 APP CADPS CADPS2 CDC25A CTNNAL1 DAG1 DGKZ DISC1 DTNA DTNB FASLG HAUS1 KCNJ12 KRT19 KRT8 MAP3K5 PGM5 SGCZ SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 TRAF3IP1 UTRN
Entrez ID		26146	1756
HPRD ID		09571	02303
Ensembl ID		ENSG00000204104	ENSG00000198947
Uniprot IDs		Q8TDR0	A1L0U9 A7E212 P11532 Q16484 Q4G0X0
PDB IDs		2EQO	1DXX 1EG3 1EG4 3UUN
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Cell Cycle Process Golgi To Plasma Membrane Protein Transport Meiotic Chromosome Condensation Cell Cycle Golgi Vesicle Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Generation Of Neurons TRIF-dependent Toll-like Receptor Signaling Pathway Neurogenesis Organelle Organization MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Signaling Cell Communication Mitotic Sister Chromatid Segregation Cell Division Establishment Of Protein Localization To Plasma Membrane Regulation Of Neurogenesis Toll-like Receptor 4 Signaling Pathway Nervous System Development Negative Regulation Of Cell Cycle Vesicle-mediated Transport Sister Chromatid Segregation Movement Of Cell Or Subcellular Component Cellular Localization Mitochondrial Calcium Ion Homeostasis Regulation Of Cell Differentiation Toll-like Receptor Signaling Pathway Membrane Organization Regulation Of Cell Development Regulation Of Neuron Differentiation Kinetochore Organization Mitotic Nuclear Division Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Metabolic Process Mitotic Chromosome Condensation Pattern Recognition Receptor Signaling Pathway Regulation Of Cell Cycle Innate Immune Response-activating Signal Transduction Cellular Response To Stimulus Response To Stimulus Activation Of Innate Immune Response Signal Transduction Cell Differentiation Protein Localization To Plasma Membrane DNA Damage Checkpoint Regulation Of Neuron Projection Development	Muscle Contraction Muscle System Process Muscle Cell Development Myofibril Assembly Actomyosin Structure Organization Organelle Assembly Cellular Component Assembly Muscle Structure Development Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Cell Development Skeletal Myofibril Assembly Synaptic Vesicle Priming Striated Muscle Cell Differentiation Organ Development Cytoskeleton Organization Organelle Organization Muscle Organ Development Positive Regulation Of Proteolysis Cell Development System Development Positive Regulation Of Peptidase Activity Cell Differentiation Involved In Embryonic Placenta Development Actin-myosin Filament Sliding Muscle Filament Sliding Movement Of Cell Or Subcellular Component Regulation Of Sodium Ion Transmembrane Transport Microtubule-based Process Actin-mediated Cell Contraction Programmed Necrotic Cell Death Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Necrotic Cell Death Multicellular Organismal Development Sarcomere Organization Neuromuscular Junction Development Synaptic Vesicle Exocytosis Anatomical Structure Development Actin Filament-based Movement Cell-cell Signaling Heart Contraction Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Calcium-dependent Cell-matrix Adhesion Regulation Of Sodium Ion Transport Anatomical Structure Morphogenesis Viral Process Apoptotic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neuron Death
Tagcloud ?		13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral	2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Difference) ?		13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral	2gamma chromosome dffry encode escape escapes eutherian homologue homologues identity inactivation kangaroo maps metatherian primates retroposon retroposons shed simian smcy spermatogenesis sxrb ube1y ubiquitously uty xp21 y zfy1 zfy2
Tagcloud (Intersection) ?