TRAF3IP1 and IL13RA1

Number of citations of the paper that reports this interaction (PMID 12935900)
4

Data Source:
HPRD (two hybrid, in vivo)

		TRAF3IP1	IL13RA1
Gene Name		TNF receptor-associated factor 3 interacting protein 1	interleukin 13 receptor, alpha 1
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Gene Ontology Annotations	Cellular Component	Centrosome Cilium Axoneme Intraciliary Transport Particle B Ciliary Basal Body Primary Cilium Ciliary Tip	Plasma Membrane Interleukin-13 Receptor Complex
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Interleukin-13 Receptor Activity
	Biological Process	Organelle Organization Neural Tube Patterning Embryonic Camera-type Eye Development Negative Regulation Of Interferon-beta Production Embryonic Heart Tube Development Post-anal Tail Morphogenesis Intraciliary Transport Cilium Assembly Embryonic Digit Morphogenesis Negative Regulation Of Defense Response To Virus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning	Positive Regulation Of Immunoglobulin Production Cell Surface Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Interleukin-13-mediated Signaling Pathway
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Intraflagellar transport
Drugs
Diseases
GWAS		Iris characteristics ( 21835309)
Protein-Protein Interactions		27 interactors: ABI2 APP CCDC93 CCNA2 CDC5L DISC1 DMD DST DTNBP1 EXOC1 FRMD4A GOLGA4 IL13RA1 IMMT MACF1 OLFM1 SFR1 SMC2 SMC3 SMC4 SNAP91 SPTBN1 TAB2 TRAF3 TRAF6 TRAK1 WAC	6 interactors: DLG4 IL13 IL4R TMEM39B TRAF3IP1 TYK2
Entrez ID		26146	3597
HPRD ID		09571	02125
Ensembl ID		ENSG00000204104	ENSG00000131724
Uniprot IDs		Q8TDR0	P78552
PDB IDs		2EQO	3BPN 3BPO 4HWB
Enriched GO Terms of Interacting Partners?		Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Cell Cycle Process Golgi To Plasma Membrane Protein Transport Meiotic Chromosome Condensation Cell Cycle Golgi Vesicle Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Response To Stress Generation Of Neurons TRIF-dependent Toll-like Receptor Signaling Pathway Neurogenesis Organelle Organization MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Signaling Cell Communication Mitotic Sister Chromatid Segregation Cell Division Establishment Of Protein Localization To Plasma Membrane Regulation Of Neurogenesis Toll-like Receptor 4 Signaling Pathway Nervous System Development Negative Regulation Of Cell Cycle Vesicle-mediated Transport Sister Chromatid Segregation Movement Of Cell Or Subcellular Component Cellular Localization Mitochondrial Calcium Ion Homeostasis Regulation Of Cell Differentiation Toll-like Receptor Signaling Pathway Membrane Organization Regulation Of Cell Development Regulation Of Neuron Differentiation Kinetochore Organization Mitotic Nuclear Division Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Metabolic Process Mitotic Chromosome Condensation Pattern Recognition Receptor Signaling Pathway Regulation Of Cell Cycle Innate Immune Response-activating Signal Transduction Cellular Response To Stimulus Response To Stimulus Activation Of Innate Immune Response Signal Transduction Cell Differentiation Protein Localization To Plasma Membrane DNA Damage Checkpoint Regulation Of Neuron Projection Development	Positive Regulation Of Macrophage Activation Regulation Of Macrophage Activation Regulation Of Immune System Process Movement Of Cell Or Subcellular Component Regulation Of Cytokine Production Cellular Response To Cytokine Stimulus Positive Regulation Of Connective Tissue Growth Factor Production Positive Regulation Of Lung Goblet Cell Differentiation Positive Regulation Of Tyrosine Phosphorylation Of Stat6 Protein Negative Regulation Of Lung Ciliated Cell Differentiation Positive Regulation Of Pancreatic Stellate Cell Proliferation Response To Cytokine Negative Regulation Of Complement-dependent Cytotoxicity Regulation Of Complement-dependent Cytotoxicity Negative Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of NAD(P)H Oxidase Activity Positive Regulation Of Protein Secretion Negative Regulation Of Cytokine Production Regulation Of Signal Transduction Negative Regulation Of Transforming Growth Factor Beta Production Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Regulation Of Grooming Behavior Regulation Of Signaling Maintenance Of Apical/basal Cell Polarity Regulation Of NAD(P)H Oxidase Activity Negative Regulation Of T-helper 1 Type Immune Response Immune Response Positive Regulation Of Cell Activation Receptor Localization To Synapse Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Defense Response Positive Regulation Of Chemokine Secretion Negative Regulation Of Receptor Internalization Positive Regulation Of Secretion Regulation Of T-helper 1 Cell Differentiation Positive Regulation Of Protein Transport Negative Regulation Of T-helper Cell Differentiation Locomotory Exploration Behavior Regulation Of Cell Proliferation Positive Regulation Of Cytokine Production Dendritic Spine Morphogenesis Negative Regulation Of Immune System Process Synaptic Vesicle Maturation Interleukin-4-mediated Signaling Pathway Maintenance Of Cell Polarity Regulation Of Lymphocyte Activation Regulation Of Proton Transport Regulation Of Protein Secretion Negative Regulation Of Alpha-beta T Cell Differentiation Microglial Cell Activation
Tagcloud ?		13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral	1b aiming balance bearing ccl24 clec4a2 decline delta depends elucidating eotaxin fold gm h37rv hour il12b immunological inb1 initiated mce1 microarrays plex post ppargamma pro qpcr switch tuberculosis uninfected
Tagcloud (Difference) ?		13r1 arches chlamydomonas cilia ciliary ciliogenesis cilium connections cytoskeletal disc1 dyf elipsa enlarged evolutionarily hedgehog homologs ift54 localizes microtubules mipt3 patterning pharyngeal polydactyly raises sequestration stat6 tnfr ventral	1b aiming balance bearing ccl24 clec4a2 decline delta depends elucidating eotaxin fold gm h37rv hour il12b immunological inb1 initiated mce1 microarrays plex post ppargamma pro qpcr switch tuberculosis uninfected
Tagcloud (Intersection) ?