TMEM30A and MAL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM30A	MAL
Description		transmembrane protein 30A	mal, T cell differentiation protein (MAL blood group)
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Phospholipid-translocating ATPase Complex	Endoplasmic Reticulum Plasma Membrane Membrane Apical Plasma Membrane Schmidt-Lanterman Incisure Plasma Membrane Raft Membrane Raft Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Aminophospholipid Flippase Activity	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Xenobiotic Transmembrane Transport Lipid Transport Positive Regulation Of Neuron Projection Development Aminophospholipid Transport Protein Localization To Endosome Phospholipid Translocation Positive Regulation Of Phospholipid Translocation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Aminophospholipid Translocation	Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Apoptotic Process Central Nervous System Development Central Nervous System Myelination Cell Differentiation Myelination Apical Protein Localization Protein Insertion Into Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: ACKR5 MAL OGT SPP1 TRIM54	81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35H1 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7
Entrez ID		55754	4118
HPRD ID		15535	01789
Ensembl ID		ENSG00000112697	ENSG00000172005
Uniprot IDs		Q9NV96	P21145
PDB IDs		6K7G 6K7H 6K7I 6K7J 6K7K 6K7L 6K7M 6K7N 6LKN 7BSP 7BSQ 7BSS 7BSU 7BSV 7BSW 7PY4 7VGI 7VGJ 7VSG 7VSH 8OX4 8OX5 8OX6 8OX7 8OX8 8OX9 8OXA 8OXB 8OXC
Enriched GO Terms of Interacting Partners?		Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Membrane Raft Polarization Negative Regulation Of Cellular Component Organization Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Response To Nutrient Protein O-acetylglucosaminyltransferase Activity Protein Localization To Paranode Region Of Axon Membrane Raft Distribution Peptidase Activator Activity Involved In Apoptotic Process Androgen Catabolic Process Cellular Response To Testosterone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Membrane Raft Localization Response To 2,3,7,8-tetrachlorodibenzodioxine Protein Localization To Axon Lipid Binding Cellular Developmental Process Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Positive Regulation Of Bone Resorption Response To Macrophage Colony-stimulating Factor Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration NSL Complex Regulation Of Transcription By Glucose Hormone Catabolic Process Apical Protein Localization	Membrane Plasma Membrane Protein Binding Gamma-delta T Cell Activation Anchoring Junction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Postsynaptic Density Membrane Cell-cell Junction Organization Bicellular Tight Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Organization Bicellular Tight Junction Assembly Tight Junction Assembly Tight Junction Organization Structural Molecule Activity Cell-cell Junction Assembly Leukocyte Activation
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