TMEM30A and ACKR5

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		TMEM30A	ACKR5
Description		transmembrane protein 30A	atypical chemokine receptor 5
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Golgi Apparatus Plasma Membrane Membrane Apical Plasma Membrane Transport Vesicle Membrane Cytoplasmic Vesicle Early Endosome Membrane Late Endosome Membrane Azurophil Granule Membrane Specific Granule Membrane Phospholipid-translocating ATPase Complex	Plasma Membrane Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Aminophospholipid Flippase Activity	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity
	Biological Process	Xenobiotic Transmembrane Transport Lipid Transport Positive Regulation Of Neuron Projection Development Aminophospholipid Transport Protein Localization To Endosome Phospholipid Translocation Positive Regulation Of Phospholipid Translocation Positive Regulation Of Protein Exit From Endoplasmic Reticulum Aminophospholipid Translocation	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS
Interacting Genes		5 interacting genes: ACKR5 MAL OGT SPP1 TRIM54	10 interacting genes: ABHD12 GOSR1 HLA-C ITGA5 MPG OGFR PLPPR3 TMEM101 TMEM30A TMUB2
Entrez ID		55754	11318
HPRD ID		15535	05605
Ensembl ID		ENSG00000112697	ENSG00000166856
Uniprot IDs		Q9NV96	O15218
PDB IDs		6K7G 6K7H 6K7I 6K7J 6K7K 6K7L 6K7M 6K7N 6LKN 7BSP 7BSQ 7BSS 7BSU 7BSV 7BSW 7PY4 7VGI 7VGJ 7VSG 7VSH 8OX4 8OX5 8OX6 8OX7 8OX8 8OX9 8OXA 8OXB 8OXC
Enriched GO Terms of Interacting Partners?		Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Membrane Raft Polarization Negative Regulation Of Cellular Component Organization Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Response To Nutrient Protein O-acetylglucosaminyltransferase Activity Protein Localization To Paranode Region Of Axon Membrane Raft Distribution Peptidase Activator Activity Involved In Apoptotic Process Androgen Catabolic Process Cellular Response To Testosterone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Membrane Raft Localization Response To 2,3,7,8-tetrachlorodibenzodioxine Protein Localization To Axon Lipid Binding Cellular Developmental Process Schmidt-Lanterman Incisure Structural Constituent Of Myelin Sheath Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Central Nervous System Myelination Positive Regulation Of Bone Resorption Response To Macrophage Colony-stimulating Factor Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Negative Regulation Of Neuron Projection Regeneration NSL Complex Regulation Of Transcription By Glucose Hormone Catabolic Process Apical Protein Localization
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