NPR1

Gene Name		natriuretic peptide receptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Guanylate Cyclase Activity Protein Kinase Activity ATP Binding GTP Binding G-protein Coupled Peptide Receptor Activity Natriuretic Peptide Receptor Activity Peptide Hormone Binding Protein Kinase Binding Hormone Binding
	Biological Process	CGMP Biosynthetic Process Protein Phosphorylation Cell Surface Receptor Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway G-protein Coupled Receptor Signaling Pathway Body Fluid Secretion Regulation Of Blood Pressure Negative Regulation Of Angiogenesis Negative Regulation Of Cell Growth Positive Regulation Of CGMP Biosynthetic Process Intracellular Signal Transduction Positive Regulation Of Urine Volume Positive Regulation Of Renal Sodium Excretion Regulation Of Vasodilation Dopamine Metabolic Process Regulation Of Vascular Permeability Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Blood Vessel Size
Pathways
Drugs		Nitroprusside Nitroglycerin Isosorbide Dinitrate Amyl Nitrite Erythrityl Tetranitrate Nesiritide
Diseases
GWAS
Protein-protein Interactions		5 interactors: ATF7IP NPPA NPPB NPPC PRKG1
Entrez ID		4881
HPRD ID		00165
Ensembl ID		ENSG00000169418
Uniprot IDs		P16066
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Blood Vessel Size Regulation Of Tube Size Receptor Guanylyl Cyclase Signaling Pathway CGMP Biosynthetic Process CGMP Metabolic Process Cyclic Purine Nucleotide Metabolic Process Cyclic Nucleotide Biosynthetic Process Blood Circulation Cyclic Nucleotide Metabolic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Ribonucleotide Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Regulation Of Vasodilation Nucleotide Metabolic Process Regulation Of Growth Nucleobase-containing Small Molecule Metabolic Process Growth Plate Cartilage Chondrocyte Proliferation Negative Regulation Of Cell Growth Regulation Of Muscle Contraction Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Blood Pressure Negative Regulation Of Oocyte Maturation Organophosphate Metabolic Process Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Oocyte Development Phosphate-containing Compound Metabolic Process Negative Regulation Of Growth Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Muscle System Process Growth Plate Cartilage Chondrocyte Differentiation Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Cardiac Muscle Contraction Response To Hypoxia Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Regulation Of Delayed Rectifier Potassium Channel Activity Response To Muscle Stretch Relaxation Of Vascular Smooth Muscle Regulation Of Cell Growth CGMP-mediated Signaling Relaxation Of Smooth Muscle Negative Regulation Of Platelet Aggregation Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Renal Sodium Excretion Negative Regulation Of Smooth Muscle Contraction Positive Regulation Of Urine Volume
Tagcloud ?		advantages asset bands bzip complemented elusive ethylene interacting interested isolating offers overexpressing oxylipin powerful proteolytically pull purification purifying researchers salicylic stimulus tag tagged tagging tap tga2 tga5 tga6 xenobiotic