GMEB1 and TRIM55

Number of citations of the paper that reports this interaction (PMID 18157088)
41

Data Source:
BioGRID (two hybrid)

		GMEB1	TRIM55
Gene Name		glucocorticoid modulatory element binding protein 1	tripartite motif containing 55
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Cytoplasm Microtubule
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Metal Ion Binding	Signal Transducer Activity Zinc Ion Binding Identical Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Signal Transduction
Pathways
Drugs
Diseases
GWAS			Response to statin therapy ( 22666496)
Protein-Protein Interactions		12 interactors: ATF7IP CASP8 CASP9 CREBBP GMEB2 NCOA2 SMAD1 SMAD3 SNIP1 TRIM55 TRIM63 UBE2I	61 interactors: ACTA1 ANKRD1 ATP5B ATXN3 ATXN3L BRAP CKM DCAF6 DES EEF1G EHHADH EIF3E ESPL1 FHL2 FLNA FLNB FLNC GFM1 GMEB1 LMCD1 MDM4 MRPL19 MRPL41 MYBPC1 MYBPC3 MYOT MYOZ1 NDUFA1 NEB NEBL NOMO1 OTUB1 OTUB2 PCGF1 PIAS1 PIAS2 PIAS3 RNF114 SQSTM1 STAM TCAP TNNI1 TNNI2 TNNI3 TRIM27 TRIM54 TRIM63 TTN UBE2D1 UBE2D2 UBE2D3 UCHL3 UCHL5 USP13 USP28 USP4 USP5 USP7 USP8 UXT YOD1
Entrez ID		10691	84675
HPRD ID		16059	05927
Ensembl ID		ENSG00000162419	ENSG00000147573
Uniprot IDs		B1AT47 B2RCN8 Q9Y692	Q9BYV6
PDB IDs		1OQJ
Enriched GO Terms of Interacting Partners?		Cellular Response To Organic Cyclic Compound Production Of MiRNAs Involved In Gene Silencing By MiRNA Gene Silencing By MiRNA Cellular Response To DsRNA Negative Regulation Of Gene Expression Posttranscriptional Gene Silencing Response To Organic Cyclic Compound Regulation Of Gene Expression, Epigenetic Primary MiRNA Processing Gene Silencing By RNA Viral Process SMAD Protein Complex Assembly Response To DsRNA Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Organic Substance Activation Of Cysteine-type Endopeptidase Activity Response To Cobalt Ion Zymogen Activation Gene Silencing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Metabolic Process Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Metabolic Process Response To Organic Substance Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Response To Dexamethasone Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Dexamethasone Signal Transduction Positive Regulation Of Cartilage Development Protein Processing Embryonic Morphogenesis Signaling Peptidyl-lysine Modification Regulation Of Cellular Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Cell Communication Regulation Of RNA Biosynthetic Process	Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Protein Deubiquitination Protein Modification By Small Protein Removal Actin Filament-based Movement Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Muscle Contraction Actin Filament-based Process Cellular Protein Catabolic Process Protein Catabolic Process Muscle System Process Protein K48-linked Deubiquitination Cellular Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Striated Muscle Cell Development Cellular Protein Metabolic Process Muscle Structure Development Muscle Cell Development Protein K63-linked Deubiquitination Myofibril Assembly Proteolysis Cellular Protein Modification Process Striated Muscle Tissue Development Cardiac Muscle Tissue Morphogenesis Striated Muscle Cell Differentiation Muscle Tissue Development Muscle Tissue Morphogenesis Actomyosin Structure Organization Muscle Organ Morphogenesis Cardiac Muscle Tissue Development Protein Metabolic Process Muscle Organ Development Protein Modification By Small Protein Conjugation Muscle Cell Differentiation Myosin Filament Assembly Catabolic Process Actin Cytoskeleton Organization Skeletal Muscle Thin Filament Assembly Cytoskeleton Organization Skeletal Myofibril Assembly Response To Muscle Stretch Heart Morphogenesis Striated Muscle Contraction Cellular Process
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