GMEB1 and ATF7IP

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		GMEB1	ATF7IP
Gene Name		glucocorticoid modulatory element binding protein 1	activating transcription factor 7 interacting protein
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Metal Ion Binding	Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		12 interactors: ATF7IP CASP8 CASP9 CREBBP GMEB2 NCOA2 SMAD1 SMAD3 SNIP1 TRIM55 TRIM63 UBE2I	68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		10691	55729
HPRD ID		16059	09811
Ensembl ID		ENSG00000162419	ENSG00000171681
Uniprot IDs		B1AT47 B2RCN8 Q9Y692	B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6
PDB IDs		1OQJ	2RPQ
Enriched GO Terms of Interacting Partners?		Cellular Response To Organic Cyclic Compound Production Of MiRNAs Involved In Gene Silencing By MiRNA Gene Silencing By MiRNA Cellular Response To DsRNA Negative Regulation Of Gene Expression Posttranscriptional Gene Silencing Response To Organic Cyclic Compound Regulation Of Gene Expression, Epigenetic Primary MiRNA Processing Gene Silencing By RNA Viral Process SMAD Protein Complex Assembly Response To DsRNA Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Organic Substance Activation Of Cysteine-type Endopeptidase Activity Response To Cobalt Ion Zymogen Activation Gene Silencing Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Metabolic Process Positive Regulation Of Endopeptidase Activity Positive Regulation Of Peptidase Activity Positive Regulation Of Metabolic Process Response To Organic Substance Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Cellular Response To Dexamethasone Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Dexamethasone Signal Transduction Positive Regulation Of Cartilage Development Protein Processing Embryonic Morphogenesis Signaling Peptidyl-lysine Modification Regulation Of Cellular Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription, DNA-templated Cell Communication Regulation Of RNA Biosynthetic Process	Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development
Tagcloud ?			acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?			acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?