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PRKAG1 and PRKAB1
Number of citations of the paper that reports this interaction (PMID
10698692
)
99
Data Source:
HPRD
(two hybrid)
PRKAG1
PRKAB1
Gene Name
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
protein kinase, AMP-activated, beta 1 non-catalytic subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Membrane
AMP-activated Protein Kinase Complex
Extracellular Vesicular Exosome
Nucleus
Cytosol
AMP-activated Protein Kinase Complex
Molecular Function
Protein Kinase Activity
AMP-activated Protein Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Binding
ATP Binding
CAMP-dependent Protein Kinase Regulator Activity
AMP Binding
Protein Kinase Binding
ADP Binding
Protein Kinase Activity
AMP-activated Protein Kinase Activity
Protein Binding
Protein Kinase Binding
Biological Process
Regulation Of Glycolytic Process
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Spermatogenesis
Insulin Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Positive Regulation Of Protein Kinase Activity
Protein Heterooligomerization
Membrane Organization
Protein Phosphorylation
Fatty Acid Biosynthetic Process
Organelle Organization
Mitochondrion Organization
Cell Cycle Arrest
Signal Transduction
Insulin Receptor Signaling Pathway
Positive Regulation Of Gene Expression
Regulation Of Protein Kinase Activity
Protein Heterooligomerization
Membrane Organization
Pathways
Organelle biogenesis and maintenance
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-mediated signalling
Regulation of Rheb GTPase activity by AMPK
mTOR signalling
Translocation of GLUT4 to the plasma membrane
IRS-related events
mTOR signalling
IGF1R signaling cascade
Mitochondrial biogenesis
IRS-related events triggered by IGF1R
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Organelle biogenesis and maintenance
Insulin receptor signalling cascade
Regulation of AMPK activity via LKB1
IRS-mediated signalling
Regulation of Rheb GTPase activity by AMPK
mTOR signalling
Translocation of GLUT4 to the plasma membrane
IRS-related events
mTOR signalling
IGF1R signaling cascade
Mitochondrial biogenesis
IRS-related events triggered by IGF1R
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
IRS-mediated signalling
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
Energy dependent regulation of mTOR by LKB1-AMPK
PKB-mediated events
PI3K Cascade
PKB-mediated events
PI3K Cascade
Signaling by Insulin receptor
Drugs
Adenosine monophosphate
Metformin
Diseases
GWAS
Protein-Protein Interactions
15 interactors:
ACACA
AP1S3
C1orf94
CBS
KCNN4
KEAP1
KRTAP10-3
KRTAP4-2
PAICS
PRKAA1
PRKAA2
PRKAB1
PRKAB2
PRKAG2
TEKT1
13 interactors:
ACACA
AGL
APP
F10
GRB2
MAP3K7
MAPK6
NDUFA7
PRKAA1
PRKAA2
PRKAG1
PRKAG2
PRKAG3
Entrez ID
5571
5564
HPRD ID
04118
04116
Ensembl ID
ENSG00000181929
ENSG00000111725
Uniprot IDs
F8W9D1
P54619
Q9Y478
PDB IDs
2UV4
2UV5
2UV6
2UV7
Enriched GO Terms of Interacting Partners
?
Carnitine Shuttle
Carnitine Transmembrane Transport
Carnitine Transport
Fatty Acid Biosynthetic Process
Quaternary Ammonium Group Transport
Long-chain Fatty Acid Transport
Fatty Acid Metabolic Process
Ammonium Transmembrane Transport
Cell Cycle Arrest
Insulin Receptor Signaling Pathway
Fatty Acid Transport
Ammonium Transport
Cellular Response To Insulin Stimulus
Lipid Biosynthetic Process
Monocarboxylic Acid Metabolic Process
Carboxylic Acid Metabolic Process
Response To Insulin
Lipid Transport
Cellular Response To Peptide Hormone Stimulus
Organic Acid Metabolic Process
Regulation Of Glycolytic Process
Lipid Localization
Cellular Response To Peptide
Monocarboxylic Acid Transport
Regulation Of Lipid Biosynthetic Process
Energy Reserve Metabolic Process
Regulation Of Fatty Acid Biosynthetic Process
Mitochondrial Transport
Membrane Organization
Organic Anion Transport
Sterol Biosynthetic Process
Negative Regulation Of Cell Cycle
Response To Peptide Hormone
Small Molecule Metabolic Process
Cellular Response To Organonitrogen Compound
Response To Peptide
Cellular Lipid Metabolic Process
Cellular Response To Hormone Stimulus
Inorganic Anion Transport
Regulation Of Generation Of Precursor Metabolites And Energy
Monovalent Inorganic Cation Transport
Anion Transport
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Fatty Acid Metabolic Process
Regulation Of Lipid Metabolic Process
Energy Derivation By Oxidation Of Organic Compounds
Carboxylic Acid Transport
Organic Acid Transport
Lipid Metabolic Process
Regulation Of Energy Homeostasis
Fatty Acid Biosynthetic Process
Insulin Receptor Signaling Pathway
Cellular Response To Insulin Stimulus
Regulation Of Glycolytic Process
Response To Insulin
Energy Derivation By Oxidation Of Organic Compounds
Energy Reserve Metabolic Process
Cellular Response To Peptide Hormone Stimulus
Carnitine Shuttle
Fatty Acid Metabolic Process
Cellular Response To Peptide
Cell Cycle Arrest
Carnitine Transmembrane Transport
Carnitine Transport
Generation Of Precursor Metabolites And Energy
Phosphorylation
Regulation Of Generation Of Precursor Metabolites And Energy
Response To Peptide Hormone
Cellular Response To Organonitrogen Compound
Protein Phosphorylation
Response To Peptide
Quaternary Ammonium Group Transport
Phosphate-containing Compound Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Response To Hormone
Lipid Biosynthetic Process
Monocarboxylic Acid Metabolic Process
Cellular Response To Hormone Stimulus
Small Molecule Metabolic Process
Sterol Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Carbohydrate Metabolic Process
Long-chain Fatty Acid Transport
Ammonium Transmembrane Transport
Sterol Biosynthetic Process
Lipid Metabolic Process
Response To Organonitrogen Compound
Negative Regulation Of Cell Cycle
Glycogen Metabolic Process
Fatty Acid Transport
Regulation Of Cell Cycle
Oxidation-reduction Process
Cellular Lipid Metabolic Process
Cellular Protein Modification Process
Ammonium Transport
Steroid Metabolic Process
Carboxylic Acid Metabolic Process
Polysaccharide Metabolic Process
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Tagcloud
?
adipor1
alter
amp
bdkrb2
changed
differential
discordant
epigenome
exercise
fh
hoxc6
mapk1
mef2a
methylation
modifies
monozygotic
muscle
myo18b
ndufc2
pairs
predispose
retinol
runx1
skeletal
t2d
thada
trib1
twin
twins
Tagcloud (Difference)
?
adipor1
alter
amp
bdkrb2
changed
differential
discordant
epigenome
exercise
fh
hoxc6
mapk1
mef2a
methylation
modifies
monozygotic
muscle
myo18b
ndufc2
pairs
predispose
retinol
runx1
skeletal
t2d
thada
trib1
twin
twins
Tagcloud (Intersection)
?