PRKAG1 and C1orf94

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PRKAG1	C1orf94
Gene Name		protein kinase, AMP-activated, gamma 1 non-catalytic subunit	chromosome 1 open reading frame 94
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Membrane AMP-activated Protein Kinase Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity AMP-activated Protein Kinase Activity CAMP-dependent Protein Kinase Activity Protein Binding ATP Binding CAMP-dependent Protein Kinase Regulator Activity AMP Binding Protein Kinase Binding ADP Binding	Protein Binding
	Biological Process	Regulation Of Glycolytic Process Protein Phosphorylation Fatty Acid Biosynthetic Process Organelle Organization Mitochondrion Organization Cell Cycle Arrest Signal Transduction Spermatogenesis Insulin Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase Activity Protein Heterooligomerization Membrane Organization
Pathways		Organelle biogenesis and maintenance Insulin receptor signalling cascade Regulation of AMPK activity via LKB1 IRS-mediated signalling Regulation of Rheb GTPase activity by AMPK mTOR signalling Translocation of GLUT4 to the plasma membrane IRS-related events mTOR signalling IGF1R signaling cascade Mitochondrial biogenesis IRS-related events triggered by IGF1R Activation of PPARGC1A (PGC-1alpha) by phosphorylation IRS-mediated signalling Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade PKB-mediated events PI3K Cascade Signaling by Insulin receptor
Drugs
Diseases
GWAS			Epilepsy (generalized) ( 22949513)
Protein-Protein Interactions		15 interactors: ACACA AP1S3 C1orf94 CBS KCNN4 KEAP1 KRTAP10-3 KRTAP4-2 PAICS PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG2 TEKT1	60 interactors: ACTN3 AES AKAP9 ATRIP ATXN1 BANP BOLA1 BOLL BYSL C1orf109 C6orf165 CARD9 CCHCR1 CCNJL CDKN2D DAB1 DAZAP2 DGCR6 DOK6 DTX2 FAM168A FAM46D GCC1 GORASP2 GRB2 GSE1 HNRNPF HOXA1 IPO11 KLHL32 LMO2 MAGED1 MAPK1IP1L MAPK9 MEIS2 MVP NFKBID NGB OAZ3 OIP5 PITX1 PLEKHB2 PRKAG1 PRR20A R3HDM2 RAD51D RBFOX1 RBFOX2 RBM47 RBPMS ROR2 SMAP2 TBX6 TNPO2 TXNDC9 UBQLN4 USO1 VENTX VPS37C YES1
Entrez ID		5571	84970
HPRD ID		04118	11310
Ensembl ID		ENSG00000181929	ENSG00000142698
Uniprot IDs		F8W9D1 P54619	Q6P1W5
PDB IDs		2UV4 2UV5 2UV6 2UV7
Enriched GO Terms of Interacting Partners?		Carnitine Shuttle Carnitine Transmembrane Transport Carnitine Transport Fatty Acid Biosynthetic Process Quaternary Ammonium Group Transport Long-chain Fatty Acid Transport Fatty Acid Metabolic Process Ammonium Transmembrane Transport Cell Cycle Arrest Insulin Receptor Signaling Pathway Fatty Acid Transport Ammonium Transport Cellular Response To Insulin Stimulus Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process Carboxylic Acid Metabolic Process Response To Insulin Lipid Transport Cellular Response To Peptide Hormone Stimulus Organic Acid Metabolic Process Regulation Of Glycolytic Process Lipid Localization Cellular Response To Peptide Monocarboxylic Acid Transport Regulation Of Lipid Biosynthetic Process Energy Reserve Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Mitochondrial Transport Membrane Organization Organic Anion Transport Sterol Biosynthetic Process Negative Regulation Of Cell Cycle Response To Peptide Hormone Small Molecule Metabolic Process Cellular Response To Organonitrogen Compound Response To Peptide Cellular Lipid Metabolic Process Cellular Response To Hormone Stimulus Inorganic Anion Transport Regulation Of Generation Of Precursor Metabolites And Energy Monovalent Inorganic Cation Transport Anion Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Fatty Acid Metabolic Process Regulation Of Lipid Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Carboxylic Acid Transport Organic Acid Transport Lipid Metabolic Process Regulation Of Energy Homeostasis	Regulation Of Phosphorus Metabolic Process Regulation Of Phosphorylation Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Radial Glia Guided Migration Of Purkinje Cell Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Phosphorylation Cell Cycle Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Arrangement Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Splicing Cell Migration In Hindbrain Regulation Of RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Response To Radiation Negative Regulation Of Signaling Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cytoplasmic Transport Neuromuscular Process RNA Metabolic Process Positive Regulation Of Protein Metabolic Process Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Abducens Nerve Formation Optokinetic Behavior Regulation Of Erythrocyte Differentiation Response To Organic Substance Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Immune System Process Regulation Of Cellular Process Organ Development System Development Cell Differentiation Nucleobase-containing Compound Metabolic Process Regulation Of Kinase Activity Response To Light Stimulus Cellular Nitrogen Compound Metabolic Process Facial Nucleus Development Cerebellum Structural Organization Putrescine Transport Golgi Vesicle Docking
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