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PRKAG1 and C1orf94
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
PRKAG1
C1orf94
Description
protein kinase AMP-activated non-catalytic subunit gamma 1
chromosome 1 open reading frame 94
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Nucleotide-activated Protein Kinase Complex
Protein-containing Complex
Molecular Function
Nucleotide Binding
AMP-activated Protein Kinase Activity
CAMP-dependent Protein Kinase Activity
Protein Binding
ATP Binding
CAMP-dependent Protein Kinase Regulator Activity
AMP Binding
Protein Kinase Regulator Activity
Protein Kinase Binding
ADP Binding
Protein-containing Complex Binding
Protein Binding
Biological Process
Regulation Of Glycolytic Process
Protein Phosphorylation
Lipid Metabolic Process
Fatty Acid Metabolic Process
Fatty Acid Biosynthetic Process
Signal Transduction
Spermatogenesis
Cellular Response To Nutrient Levels
Cellular Response To Glucose Starvation
Regulation Of Carbon Utilization
Positive Regulation Of Gluconeogenesis
Import Into Nucleus
Regulation Of Cell Cycle
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Macroautophagy
Activation of PPARGC1A (PGC-1alpha) by phosphorylation
Energy dependent regulation of mTOR by LKB1-AMPK
TP53 Regulates Metabolic Genes
Regulation of TP53 Activity through Phosphorylation
Lipophagy
Activation of AMPK downstream of NMDARs
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs
Adenosine phosphate
Acetylsalicylic acid
Fostamatinib
Diseases
GWAS
Adult body size (
32376654
)
Bipolar disorder (
31043756
)
Body mass index (
29273807
)
HDL cholesterol (
30275531
)
Pulse pressure (
27618447
)
Red cell distribution width (
32888494
)
Systolic blood pressure (
27618447
30578418
)
Generalized epilepsy (
22949513
)
Lateral ventricle temporal horn volume (
31530798
)
Pediatric nonalcoholic steatohepatitis (
28918882
)
Sleep duration (short sleep) (
30846698
)
Interacting Genes
31 interacting genes:
ACACA
AP1S3
C1orf94
CBS
CRBN
EIF3G
KCNN4
KEAP1
KLHL20
KRTAP1-1
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP4-12
KRTAP4-2
KRTAP9-2
KRTAP9-8
MEOX1
MEOX2
PAICS
PAX6
PLEKHF2
PRKAA1
PRKAA2
PRKAB1
PRKAB2
PRKAG2
PRKDC
TEKT1
TNFAIP1
89 interacting genes:
ACTN3
AIRIM
AKAP9
ATRIP
ATXN1
ATXN1L
BANP
BOLA1
BOLA2
BOLA2B
BOLL
BYSL
CAMK2A
CARD9
CCHCR1
CCNJL
CDKN2D
CFAP206
CHERP
CLK1
CRK
CRYBA4
DAB1
DAZAP2
DGCR6
DMRTB1
DOK6
DTX2
FAM168A
FHL3
GCC1
GORASP2
GRB2
GSE1
HGS
HNRNPF
HSF2BP
INTS11
IPO11
KLHL32
KRTAP6-2
KRTAP7-1
KRTAP8-1
LCE2C
LMO2
MAGED1
MAPK1IP1L
MAPK9
MEIS2
MVP
NFKBID
NGB
NR3C1
OAZ3
OIP5
PITX1
PLA2G10
PLEKHB2
PRKAG1
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
R3HDM2
RAD51D
RBFOX1
RBFOX2
RBM47
RBPMS
RFX2
RHOXF2
ROR2
SMAP2
SS18L1
TBX6
TENT5D
TLE5
TNPO2
TNS2
TSC1
TXNDC9
UBQLN2
UBQLN4
USO1
VENTX
VPS37C
YES1
Entrez ID
5571
84970
HPRD ID
04118
11310
Ensembl ID
ENSG00000181929
ENSG00000142698
Uniprot IDs
F8VYY9
P54619
Q6P1W5
PDB IDs
2UV4
2UV5
2UV6
2UV7
4CFE
4CFF
4RER
4REW
4ZHX
5EZV
5ISO
6B1U
6B2E
6C9F
6C9G
6C9H
6C9J
7JHG
7JHH
7JIJ
7M74
7MYJ
8BIK
Enriched GO Terms of Interacting Partners
?
Keratin Filament
Nucleotide-activated Protein Kinase Complex
Intermediate Filament
AMP-activated Protein Kinase Activity
Carboxylic Acid Biosynthetic Process
Cytosol
Fatty Acid Biosynthetic Process
Small Molecule Biosynthetic Process
Histone H2BS36 Kinase Activity
[hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Prostaglandin Stimulus
Fatty Acid Metabolic Process
Response To Prostaglandin E
Protein Localization To Lipid Droplet
Monocarboxylic Acid Metabolic Process
Somite Specification
Carboxylic Acid Metabolic Process
Negative Regulation Of Tubulin Deacetylation
Negative Regulation Of Hepatocyte Apoptotic Process
Organic Acid Metabolic Process
Regulation Of Tubulin Deacetylation
Lipid Droplet Disassembly
Sterol Biosynthetic Process
Cellular Response To Glucose Starvation
Regulation Of Generation Of Precursor Metabolites And Energy
Cellular Response To Nutrient Levels
Regulation Of Glycolytic Process
Phosphatidylethanolamine Biosynthetic Process
Cul3-RING Ubiquitin Ligase Complex
Regulation Of Protein Deacetylation
Regulation Of Stress Granule Assembly
Protein Homotetramerization
HMG Box Domain Binding
Regulation Of Carbohydrate Catabolic Process
Response To Nutrient Levels
L-serine Metabolic Process
Hair Cycle
Segment Specification
Somite Development
Regulation Of ATP Metabolic Process
Lipid Biosynthetic Process
Fatty Acid Homeostasis
Hepatocyte Apoptotic Process
Protein Homooligomerization
Regulation Of Purine Nucleotide Metabolic Process
Steroid Biosynthetic Process
Protein Tetramerization
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Phosphatidylcholine Biosynthetic Process
Protein Binding
Identical Protein Binding
Iron-sulfur Cluster Assembly Complex
Nucleus
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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