PRKAB1 and NDUFA7

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		PRKAB1	NDUFA7
Name		protein kinase AMP-activated non-catalytic subunit beta 1	NADH:ubiquinone oxidoreductase subunit A7
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex Protein-containing Complex	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Signal Transduction Cellular Response To Nutrient Levels Nail Development Positive Regulation Of Cold-induced Thermogenesis	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)	Respiratory electron transport Complex I biogenesis
Drugs		Adenosine phosphate Adenosine phosphate Metformin Acetylsalicylic acid Fostamatinib	NADH
GWAS		Basophil count ( 32888494 ) Inflammatory bowel disease ( 26192919 ) Lymphocyte percentage of white cells ( 32888494 ) Mitochondrial heteroplasmy measurement ( 33731350 ) Monocyte count ( 32888494 ) Neutrophil count ( 32888494 ) Plateletcrit ( 32888494 ) Ulcerative colitis ( 26192919 ) White blood cell count ( 32888494 )	No GWAS studies recorded
Interacting Genes		13 interacting genes: ACACA AGL APP F10 GRB2 MAP3K7 MAPK6 NDUFA7 PRKAA1 PRKAA2 PRKAG1 PRKAG2 SLC31A1	8 interacting genes: ELAC2 LMO1 MDFI PRKAB1 RTP2 STARD9 TTPA UPF2
Entrez ID		5564	4701
HPRD ID		04116	11885
Ensembl ID		ENSG00000111725	ENSG00000267855
Uniprot IDs		Q9Y478	O95182
PDB IDs		4CFE 4CFF 4ZHX 5EZV 5ISO 6B1U 6C9F 6C9G 6C9H 6C9J 7MYJ 8BIK	5XTB 5XTD 5XTH 5XTI
GO Terms Enriched among Interactors		AMP-activated Protein Kinase Activity Nucleotide-activated Protein Kinase Complex Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Fatty Acid Biosynthetic Process Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Glucose Starvation Positive Regulation Of Small Molecule Metabolic Process Cellular Response To Prostaglandin E Stimulus Positive Regulation Of Glycolytic Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Cellular Response To Prostaglandin Stimulus Carboxylic Acid Biosynthetic Process Response To Prostaglandin E Phosphate-containing Compound Metabolic Process Regulation Of Carbon Utilization Fatty Acid Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of ATP Metabolic Process Regulation Of Small Molecule Metabolic Process Protein Localization To Lipid Droplet Sterol Biosynthetic Process Negative Regulation Of Tubulin Deacetylation CAMP-dependent Protein Kinase Activity Negative Regulation Of Hepatocyte Apoptotic Process Cellular Response To Starvation Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly CAMP-dependent Protein Kinase Regulator Activity Small Molecule Biosynthetic Process Protein Kinase Binding Monocarboxylic Acid Metabolic Process Response To Starvation Response To Nutrient Levels Phosphatidylethanolamine Biosynthetic Process ATP Binding Organophosphate Biosynthetic Process Lipid Biosynthetic Process Regulation Of Protein Deacetylation Regulation Of Stress Granule Assembly Cellular Response To Nutrient Levels Steroid Biosynthetic Process AMP Binding Positive Regulation Of TOR Signaling Response To Hormone Intracellular Copper Ion Homeostasis Protein Kinase Regulator Activity	None