YJU2 and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YJU2	TFCP2
Description		YJU2 splicing factor homolog	transcription factor CP2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 1 Spliceosome	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Interacting Genes		22 interacting genes: BANP BRAP CCDC57 CEP70 DRC4 EMILIN1 FRS2 GOLGA2 GOLGA6A JADE1 KAT5 LNX2 MAD1L1 MEOX2 REL TFCP2 TRIM15 TRIM21 TRIM27 ZNF143 ZNF526 ZNF829	73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		55702	7024
HPRD ID		08546	01790
Ensembl ID		ENSG00000105248	ENSG00000135457
Uniprot IDs		Q9BW85	Q12800
PDB IDs		5YZG 6ZYM 7A5P 8I0W
Enriched GO Terms of Interacting Partners?		Suppression Of Viral Release By Host Regulation Of Type I Interferon Production Canonical NF-kappaB Signal Transduction Zinc Ion Binding Transcription Coactivator Activity Positive Regulation Of Mitotic Sister Chromatid Segregation Histone H4K16 Acetyltransferase Activity Golgi Cis Cisterna Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Viral Process Protein K63-linked Ubiquitination Organelle Disassembly Regulation Of Metaphase Plate Congression Positive Regulation Of Biosynthetic Process Identical Protein Binding Negative Regulation Of Viral Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Viral Transcription Ubiquitin-protein Transferase Activity Attachment Of Mitotic Spindle Microtubules To Kinetochore Membraneless Organelle Assembly Histone Acetyltransferase Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Microtubule Nucleation DNA Binding Regulation Of Viral Process Positive Regulation Of Chromosome Segregation Positive Regulation Of Cell Cycle Spindle Pole Ubiquitin Protein Ligase Activity Mitotic Spindle Pole Attachment Of Spindle Microtubules To Kinetochore Regulation Of Autophagy Innate Immune Response MAD1 Complex Histone H2AK5 Acetyltransferase Activity Regulation Of Protein Binding Positive Regulation Of Autophagy Negative Regulation Of Type I Interferon Production Positive Regulation Of Metabolic Process Cytoskeleton Cis-Golgi Network Organelle Assembly DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Microtubule Cytoskeleton Organization Defense Response To Other Organism Defense Response To Symbiont	Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic
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