YJU2 and ZNF143

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		YJU2	ZNF143
Description		YJU2 splicing factor homolog	zinc finger protein 143
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U2-type Catalytic Step 1 Spliceosome	Nucleus Nucleoplasm
	Molecular Function	Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Generation Of Catalytic Spliceosome For First Transesterification Step MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Positive Regulation Of SnRNA Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway	RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 3 Promoter
Drugs
Diseases
GWAS			Cutaneous squamous cell carcinoma ( 32041948) Height ( 31562340) Hip circumference ( 28552196)
Interacting Genes		22 interacting genes: BANP BRAP CCDC57 CEP70 DRC4 EMILIN1 FRS2 GOLGA2 GOLGA6A JADE1 KAT5 LNX2 MAD1L1 MEOX2 REL TFCP2 TRIM15 TRIM21 TRIM27 ZNF143 ZNF526 ZNF829	21 interacting genes: EAF1 ENKD1 EXOSC1 FAM90A1 FHL2 IL16 IQUB LIN54 LMO1 LMO3 NUDT22 POGZ SNRPB SPANXN3 SUOX TAB2 TCAF1 TSC22D2 YJU2 ZNF438 ZNF512B
Entrez ID		55702	7702
HPRD ID		08546	04578
Ensembl ID		ENSG00000105248	ENSG00000166478
Uniprot IDs		Q9BW85	P52747
PDB IDs		5YZG 6ZYM 7A5P 8I0W
Enriched GO Terms of Interacting Partners?		Suppression Of Viral Release By Host Regulation Of Type I Interferon Production Canonical NF-kappaB Signal Transduction Zinc Ion Binding Transcription Coactivator Activity Positive Regulation Of Mitotic Sister Chromatid Segregation Histone H4K16 Acetyltransferase Activity Golgi Cis Cisterna Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of Viral Process Protein K63-linked Ubiquitination Organelle Disassembly Regulation Of Metaphase Plate Congression Positive Regulation Of Biosynthetic Process Identical Protein Binding Negative Regulation Of Viral Transcription Positive Regulation Of RNA Metabolic Process Regulation Of Viral Transcription Ubiquitin-protein Transferase Activity Attachment Of Mitotic Spindle Microtubules To Kinetochore Membraneless Organelle Assembly Histone Acetyltransferase Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Microtubule Nucleation DNA Binding Regulation Of Viral Process Positive Regulation Of Chromosome Segregation Positive Regulation Of Cell Cycle Spindle Pole Ubiquitin Protein Ligase Activity Mitotic Spindle Pole Attachment Of Spindle Microtubules To Kinetochore Regulation Of Autophagy Innate Immune Response MAD1 Complex Histone H2AK5 Acetyltransferase Activity Regulation Of Protein Binding Positive Regulation Of Autophagy Negative Regulation Of Type I Interferon Production Positive Regulation Of Metabolic Process Cytoskeleton Cis-Golgi Network Organelle Assembly DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Microtubule Cytoskeleton Organization Defense Response To Other Organism Defense Response To Symbiont
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