KRTAP10-5 and LIMS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP10-5	LIMS2
Description		keratin associated protein 10-5	LIM zinc finger domain containing 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Membrane Anchoring Junction
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Metal Ion Binding
	Biological Process		Integrin-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Cell-cell Junction Organization Neural Precursor Cell Proliferation Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cholangiocyte Proliferation Cholangiocyte Proliferation Negative Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Hepatocyte Proliferation Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Keratinization	Cell-extracellular matrix interactions
Drugs
Diseases
GWAS			Alzheimer's disease (cognitive decline) ( 23535033) Type 2 diabetes ( 25483131)
Interacting Genes		159 interacting genes: ADAMTSL4 AEN ALDH3B1 AMOTL2 BCL6B BMP7 BYSL C11orf87 C17orf50 CARD9 CATSPER1 CHRD CNNM3 CRCT1 CREB5 CYSRT1 DHX57 ECE1 EIF4E2 ENKD1 FAM74A4 FAM76B FARS2 FBXO34 FCHO1 GATA1 GLIDR GLRX3 GNE GOLGA8EP GPRIN2 HHEX HOXA1 HPCAL1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP13-1 KRTAP13-2 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 LIMS2 LUZP4 MEOX2 MOBP MT1DP MXI1 NAA10 NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR4A1 NR4A3 NTAQ1 NUFIP2 OTX1 POM121L8P POU4F2 PRKAB2 PRKAG1 PRR13 RBP3 SCNM1 SHFL SLC23A1 SLC6A20 SMCP SPACA9 SPATA3 SPRY1 SPRY2 STK16 TBC1D16 THAP10 TNP2 TNS2 TRIM42 TRPV6 TULP3 TXNDC5 TYMSOS UTP23 WT1 WT1-AS YY1 ZBTB24 ZBTB48 ZFYVE21 ZNF124 ZNF20 ZNF264 ZNF273 ZNF286A ZNF32 ZNF320 ZNF329 ZNF34 ZNF417 ZNF433 ZNF439 ZNF440 ZNF559 ZNF572 ZNF578 ZNF587 ZNF670 ZNF679 ZNF696 ZNF697 ZNF707 ZNF785 ZNF792 ZSCAN21 ZSCAN26	18 interacting genes: APP CALCOCO2 GOLGA2 HIPK3 HOXA1 HRH1 ILK KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 LMNA MDFI MTUS2 NOTCH2NLA RCHY1 TRIM55 TRIM63
Entrez ID		386680	55679
HPRD ID		11191	06389
Ensembl ID		ENSG00000241123	ENSG00000072163
Uniprot IDs		P60370	B3KNZ3 Q7Z4I7
PDB IDs			3IXE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Tissue Development Protein Binding Zinc Ion Binding Hair Cycle DNA Binding Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Glomerular Mesangial Cell Proliferation Sequence-specific Double-stranded DNA Binding	Intermediate Filament Keratin Filament Visual Behavior
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