KRTAP10-5 and HHEX

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-5	HHEX
Gene Name		keratin associated protein 10-5	hematopoietically expressed homeobox
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Nucleus Cytoplasm Protein-DNA Complex
	Molecular Function		RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Chromatin Binding Protein Binding Transcription Factor Binding Eukaryotic Initiation Factor 4E Binding DNA Binding, Bending TBP-class Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Repressing Transcription Factor Binding HMG Box Domain Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Vasculogenesis In Utero Embryonic Development Myeloid Leukocyte Differentiation Transcription, DNA-templated MRNA Export From Nucleus Endoderm Development Cell Proliferation Response To Wounding Anterior/posterior Pattern Specification Negative Regulation Of Transcription By Transcription Factor Localization Negative Regulation Of Transcription By Competitive Promoter Binding Wnt Signaling Pathway Negative Regulation Of Angiogenesis Poly(A)+ MRNA Export From Nucleus Interkinetic Nuclear Migration Cell Differentiation Positive Regulation Of Wnt Signaling Pathway B Cell Differentiation Thyroid Gland Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Pancreas Development Protein Localization To Nucleus Embryonic Heart Tube Development Multicellular Organism Growth Regulation Of Cell Proliferation Response To Peptide Hormone Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Forebrain Morphogenesis Primary Lung Bud Formation Gall Bladder Development Hepatic Duct Development Hepatoblast Differentiation Hepatocyte Differentiation DNA Conformation Change Primitive Streak Formation
Pathways
Drugs
Diseases
GWAS			Dehydroepiandrosterone sulphate levels ( 21533175) Multiple sclerosis ( 21833088) Type 2 diabetes ( 18372903 17293876 22693455 20862305 20581827 19401414 17463246 17463248 17463249)
Protein-Protein Interactions		108 interactors: ADAMTSL4 AEN ALDH3B1 AMOTL2 BCL6B BMP7 BYSL C11orf87 C19orf66 C9orf9 CARD9 CHRD CNNM3 CREB5 DHX57 ECE1 EIF4E2 ENKD1 FAM74A4 FAM76B FARS2 GATA1 GLIDR GLRX3 GNE GOLGA8EP HHEX HOXA1 HPCAL1 KRTAP10-3 KRTAP10-7 KRTAP12-1 KRTAP12-2 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LIMS2 LUZP4 MEOX2 MOBP MT1DP MXI1 NAA10 NOTCH2NL NPDC1 NR4A1 NUFIP2 OTX1 POM121L8P PRKAB2 PRR13 PVRL2 SCNM1 SLC23A1 SLC6A20 SMCP SPATA3 SPRY1 SPRY2 STK16 TBC1D16 THAP10 TNP2 TNS2 TRPV6 TULP3 TXNDC5 TYMSOS UTP23 WDYHV1 WT1-AS ZBTB24 ZBTB48 ZFYVE21 ZNF20 ZNF264 ZNF273 ZNF286A ZNF32 ZNF320 ZNF329 ZNF34 ZNF417 ZNF433 ZNF439 ZNF559 ZNF572 ZNF587 ZNF670 ZNF679 ZNF697 ZNF707 ZNF785 ZNF792 ZSCAN21 ZSCAN26	15 interactors: EFEMP2 GATA2 GATA6 JUN KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP4-12 PML PSMA3 SOX10 SOX8 TLE1 TRMT6
Entrez ID		386680	3087
HPRD ID		11191	06829
Ensembl ID
Uniprot IDs		P60370	Q03014
PDB IDs			2E1O
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Biosynthetic Process Keratinization Regulation Of Nitrogen Compound Metabolic Process Keratinocyte Differentiation Regulation Of Metabolic Process Epidermal Cell Differentiation Epithelium Development Epidermis Development Cellular Process Cellular Metabolic Process Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Skin Development Tissue Development Regulation Of Cellular Process Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Organ Development Regulation Of Neurotrophin TRK Receptor Signaling Pathway Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Embryonic Neurocranium Morphogenesis Penetration Of Zona Pellucida Embryo Development Epithelial Cell Differentiation Epithelial Tube Branching Involved In Lung Morphogenesis Bud Elongation Involved In Lung Branching Pattern Specification Process Embryonic Organ Development Negative Regulation Of Protein Serine/threonine Kinase Activity Embryonic Morphogenesis Lung Morphogenesis Anterior/posterior Pattern Specification Respiratory Tube Development Negative Regulation Of Ras GTPase Activity Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Gene Expression Regulation Of Apoptotic Process Positive Regulation Of Cell Differentiation Transcription From RNA Polymerase II Promoter Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Organ Morphogenesis Positive Regulation Of Cell Cycle Arrest RNA Metabolic Process Cell Fate Commitment SMAD Protein Import Into Nucleus Tube Development Positive Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of Cell Cycle Arrest RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of Cell Proliferation Anatomical Structure Morphogenesis Macromolecule Biosynthetic Process Enteric Nervous System Development Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cell Maturation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Gland Development In Utero Embryonic Development Epithelium Development Organ Development Epithelial Cell Differentiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Wnt Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Angiogenesis Positive Regulation Of Cell Cycle Process Regulation Of Gene Expression
Tagcloud ?			beyond circulation clp definitive deleted dendritic deregulated developmental functioning hematopoiesis hematopoietic hematopoietically homeobox knockout lineages lymphoid nk null overexpressed precursors progenitors progressive regulators rescue spleen stem subsets tolerated transitional
Tagcloud (Difference) ?			beyond circulation clp definitive deleted dendritic deregulated developmental functioning hematopoiesis hematopoietic hematopoietically homeobox knockout lineages lymphoid nk null overexpressed precursors progenitors progressive regulators rescue spleen stem subsets tolerated transitional
Tagcloud (Intersection) ?