ZNF232 and PPCDC

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ZNF232	PPCDC
Gene Name		zinc finger protein 232	phosphopantothenoylcysteine decarboxylase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding	Phosphopantothenoylcysteine Decarboxylase Activity
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Coenzyme Biosynthetic Process Coenzyme A Biosynthetic Process Pantothenate Metabolic Process Small Molecule Metabolic Process
Pathways			Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Vitamin B5 (pantothenate) metabolism Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Coenzyme A biosynthesis Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS			Blood trace element (Zn levels) ( 23720494) Caffeine consumption ( 21490707)
Protein-Protein Interactions		6 interactors: EMD MTUS2 NR2E3 PPCDC YY1 ZNF446	8 interactors: CENPT DBI FOXR1 PPIG SREK1IP1 TXN2 WDYHV1 ZNF232
Entrez ID		7775	60490
HPRD ID		15755	14377
Ensembl ID		ENSG00000167840	ENSG00000138621
Uniprot IDs		I3L4J6 Q9UNY5	H3BRQ0 Q96CD2
PDB IDs			1QZU
Enriched GO Terms of Interacting Partners?		Response To Prostaglandin F Eye Morphogenesis Transcription From RNA Polymerase II Promoter Positive Regulation Of Rhodopsin Gene Expression Regulation Of Rhodopsin Gene Expression Mitotic Nuclear Envelope Reassembly Response To Light Stimulus Response To UV-C Negative Regulation Of Catenin Import Into Nucleus Camera-type Eye Development Nuclear Envelope Reassembly Pantothenate Metabolic Process Eye Development Positive Regulation Of Protein Export From Nucleus Response To Radiation Coenzyme A Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Catenin Import Into Nucleus Coenzyme A Metabolic Process Nucleobase-containing Compound Metabolic Process Sensory Organ Development Regulation Of Protein Export From Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Mitotic Nuclear Envelope Disassembly Negative Regulation Of Cell Proliferation Negative Regulation Of Fibroblast Proliferation Transcription, DNA-templated Eye Photoreceptor Cell Development Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nuclear Envelope Disassembly Photoreceptor Cell Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Photoreceptor Cell Differentiation Response To Organic Substance
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