POMGNT1 and SOX6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POMGNT1	SOX6
Gene Name		protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	SRY (sex determining region Y)-box 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane	Nucleus Nucleoplasm
	Molecular Function	Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,3-N-acetylglucosaminyltransferase Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Protein O-linked Glycosylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cell Morphogenesis In Utero Embryonic Development Transcription, DNA-templated Regulation Of Transcription, DNA-templated Muscle Organ Development Post-embryonic Development Gene Silencing Oligodendrocyte Cell Fate Specification Positive Regulation Of Chondrocyte Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Astrocyte Differentiation Erythrocyte Development Cartilage Development Cardiac Muscle Cell Differentiation Positive Regulation Of Cartilage Development Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Mesenchymal Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Bone mineral density ( 22504420) Bone mineral density (hip) ( 19801982) Capecitabine sensitivity ( 22864933) Obesity and osteoporosis ( 19714249) Wrist bone mass ( 21104366)
Protein-Protein Interactions		5 interactors: BRCA1 CXCL8 LNX1 SOX6 ZBTB18	12 interactors: CENPK CTBP2 DAZAP2 HDAC1 POMGNT1 SOX5 SUMO1 SUMO2 SUMO3 TRIP12 UBE2J1 ZNF184
Entrez ID		55624	55553
HPRD ID		09493	06267
Ensembl ID		ENSG00000085998	ENSG00000110693
Uniprot IDs		F5H827 Q8WZA1	P35712
PDB IDs
Enriched GO Terms of Interacting Partners?		Embryo Development Cellular Response To Tumor Necrosis Factor Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Response To Tumor Necrosis Factor Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Positive Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Transcription, DNA-templated Cellular Response To Indole-3-methanol Negative Regulation Of Nucleic Acid-templated Transcription Homeostasis Of Number Of Cells Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Centriole Replication Regulation Of Mesenchymal Stem Cell Differentiation Dosage Compensation By Inactivation Of X Chromosome Muscle Organ Development Oligodendrocyte Cell Fate Specification Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Protein K6-linked Ubiquitination Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Striated Muscle Tissue Development Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Histone H3-K9 Acetylation Muscle Tissue Development Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Negative Regulation Of Cell Cycle Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Induction Of Positive Chemotaxis Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Regulation Of Transcription From RNA Polymerase II Promoter Glial Cell Fate Commitment Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation	Protein Sumoylation Protein Modification By Small Protein Conjugation Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Protein Catabolic Process Post-translational Protein Modification Positive Regulation Of Protein Catabolic Process Cellular Protein Modification Process Peptidyl-lysine Modification Positive Regulation Of Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process ATP-dependent Chromatin Remodeling Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Peptidyl-amino Acid Modification Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Cellular Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Histone H2A K63-linked Ubiquitination Negative Regulation Of Cellular Metabolic Process Regulation Of Histone Ubiquitination PML Body Organization Negative Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Mesenchymal Stem Cell Differentiation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Timing Of Neuron Differentiation Protein Localization To Nuclear Pore Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Chromatin Binding Regulation Of Mesenchymal Stem Cell Differentiation Protein Localization To Nucleus Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Proteolysis Protein Localization To Nuclear Envelope Negative Regulation Of Double-strand Break Repair Cellular Response To Transforming Growth Factor Beta Stimulus Chromatin Remodeling Response To Transforming Growth Factor Beta Negative Regulation Of DNA Repair
Tagcloud ?		176t 2059dupc boy carbohydrate concurred confirming damaging delay differing duplication dystroglycan dystroglycanopathies dystroglycanopathy dystrophy genetically glycosylation immunofluorescence involvements moiety muscular ocular platforms pomt2 premature severities silico substitution termination	11p15 13q21 15q15 17q23 19q13 20q11 avian b4galt5 betaglcnac cytoscan elongation epb41l1 erb erbb4 erythroblastic erythrocyte gains gal galactosyltransferase helicase heterozygozity loh peritoneal polypeptide rtel1 sry udp xp22 xq26
Tagcloud (Difference) ?		176t 2059dupc boy carbohydrate concurred confirming damaging delay differing duplication dystroglycan dystroglycanopathies dystroglycanopathy dystrophy genetically glycosylation immunofluorescence involvements moiety muscular ocular platforms pomt2 premature severities silico substitution termination	11p15 13q21 15q15 17q23 19q13 20q11 avian b4galt5 betaglcnac cytoscan elongation epb41l1 erb erbb4 erythroblastic erythrocyte gains gal galactosyltransferase helicase heterozygozity loh peritoneal polypeptide rtel1 sry udp xp22 xq26
Tagcloud (Intersection) ?