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SOX6
Gene Name
SRY (sex determining region Y)-box 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Molecular Function
DNA Binding
Sequence-specific DNA Binding Transcription Factor Activity
Protein Binding
Sequence-specific DNA Binding
Transcription Regulatory Region DNA Binding
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cell Morphogenesis
In Utero Embryonic Development
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Muscle Organ Development
Post-embryonic Development
Gene Silencing
Oligodendrocyte Cell Fate Specification
Positive Regulation Of Chondrocyte Differentiation
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Astrocyte Differentiation
Erythrocyte Development
Cartilage Development
Cardiac Muscle Cell Differentiation
Positive Regulation Of Cartilage Development
Cellular Response To Transforming Growth Factor Beta Stimulus
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Bone mineral density (
22504420
)
Bone mineral density (hip) (
19801982
)
Capecitabine sensitivity (
22864933
)
Obesity and osteoporosis (
19714249
)
Wrist bone mass (
21104366
)
Protein-protein Interactions
12 interactors:
CENPK
CTBP2
DAZAP2
HDAC1
POMGNT1
SOX5
SUMO1
SUMO2
SUMO3
TRIP12
UBE2J1
ZNF184
Entrez ID
55553
HPRD ID
06267
Ensembl ID
ENSG00000110693
Uniprot IDs
P35712
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Sumoylation
Protein Modification By Small Protein Conjugation
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Post-translational Protein Modification
Positive Regulation Of Protein Catabolic Process
Cellular Protein Modification Process
Peptidyl-lysine Modification
Positive Regulation Of Metabolic Process
Positive Regulation Of Proteolysis
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
ATP-dependent Chromatin Remodeling
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Catabolic Process
Peptidyl-amino Acid Modification
Regulation Of Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Transcription, DNA-templated
Cellular Protein Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Metabolic Process
Negative Regulation Of Histone H2A K63-linked Ubiquitination
Negative Regulation Of Cellular Metabolic Process
Regulation Of Histone Ubiquitination
PML Body Organization
Negative Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Timing Of Neuron Differentiation
Protein Localization To Nuclear Pore
Regulation Of Protein K63-linked Ubiquitination
Positive Regulation Of Chromatin Binding
Regulation Of Mesenchymal Stem Cell Differentiation
Protein Localization To Nucleus
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Regulation Of Proteolysis
Protein Localization To Nuclear Envelope
Negative Regulation Of Double-strand Break Repair
Cellular Response To Transforming Growth Factor Beta Stimulus
Chromatin Remodeling
Response To Transforming Growth Factor Beta
Negative Regulation Of DNA Repair
Tagcloud
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11p15
13q21
15q15
17q23
19q13
20q11
avian
b4galt5
betaglcnac
cytoscan
elongation
epb41l1
erb
erbb4
erythroblastic
erythrocyte
gains
gal
galactosyltransferase
helicase
heterozygozity
loh
peritoneal
polypeptide
rtel1
sry
udp
xp22
xq26