PRR5 and DESI1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRR5	DESI1
Description		proline rich 5	desumoylating isopeptidase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol TORC2 Complex	Nucleus Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Peptidase Activity Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity DeSUMOylase Activity Identical Protein Binding Long-chain Fatty Acyl-CoA Hydrolase Activity Importin-alpha Family Protein Binding
	Biological Process	Cytoskeleton Organization Positive Regulation Of Cell Growth Cellular Response To Nutrient Levels TORC2 Signaling Negative Regulation Of Apoptotic Process Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction	Proteolysis Protein Export From Nucleus Protein Desumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Depalmitoylation
Pathways		PIP3 activates AKT signaling CD28 dependent PI3K/Akt signaling VEGFR2 mediated vascular permeability Constitutive Signaling by AKT1 E17K in Cancer Regulation of TP53 Degradation High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs
Diseases
GWAS		Binge eating behaviour in bipolar disorder ( 24882193 29391396) Electroencephalographic traits in alcoholism ( 22554406)	General cognitive ability ( 29844566) Meat-related diet ( 32066663) Neuroticism ( 29255261) Refractive error ( 32231278)
Interacting Genes		5 interacting genes: CTNNA3 DESI1 GPSM3 HGS USHBP1	32 interacting genes: ABI3 AGR3 CCDC158 CDIP1 CDSN CTAG1A CTAG1B CTAG2 DAZAP2 ERP29 EVI2B FGF7 GOLM1 KLRF1 MEOX2 NME3 NT5C3A PRR5 RNF4 RPS27A SHISA4 SHISA5 SMIM21 TAS2R41 UBA52 UBB UBC UBQLN1 UBQLNL UHRF2 XPO1 ZBTB46
Entrez ID		55615	27351
HPRD ID		18696	18590
Ensembl ID		ENSG00000186654	ENSG00000100418
Uniprot IDs		P85299	Q6ICB0
PDB IDs			3EBQ
Enriched GO Terms of Interacting Partners?		Chemoattraction Of Dopaminergic Neuron Axon Establishment Or Maintenance Of Polarity Of Embryonic Epithelium Lobar Bronchus Development Trachea Cartilage Morphogenesis Renal Outer Medulla Development Outer Medullary Collecting Duct Development Bronchus Development Chemoattraction Of Axon Metanephric Loop Of Henle Development Inner Medullary Collecting Duct Development Renal Inner Medulla Development ESCRT-0 Complex	Protein Tag Activity TRNA Threonylcarbamoyladenosine Metabolic Process Modification-dependent Protein Catabolic Process Endocytic Vesicle Membrane Ubiquitin Protein Ligase Binding Mitochondrial Outer Membrane Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Regulation Of Granulocyte Differentiation Protein Modification By Small Protein Conjugation Vesicle
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?