PI4K2A and CD63

Number of citations of the paper that reports this interaction (PubMedID 9006891)
0

Data Source:
HPRD (in vivo)

		PI4K2A	CD63
Description		phosphatidylinositol 4-kinase type 2 alpha	CD63 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Lysosomal Membrane Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endosome Membrane Membrane Dendrite BLOC-1 Complex Cytoplasmic Vesicle Early Endosome Membrane Growing Cell Tip Presynaptic Membrane Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Membrane Raft Synapse Presynaptic Active Zone Glutamatergic Synapse	Extracellular Region Extracellular Space Nucleoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Multivesicular Body Plasma Membrane Cell Surface Endosome Membrane Membrane Platelet Dense Granule Membrane Late Endosome Membrane Endosome Lumen Vesicle Multivesicular Body Membrane Protein-containing Complex Azurophil Granule Membrane Melanosome Extracellular Exosome Multivesicular Body, Internal Vesicle
	Molecular Function	Nucleotide Binding Magnesium Ion Binding 1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity AP-3 Adaptor Complex Binding	Protein Binding Protein-containing Complex Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Golgi Organization Endosome Organization Phosphatidylinositol Phosphate Biosynthetic Process	Positive Regulation Of Receptor Internalization Cell-matrix Adhesion Negative Regulation Of Epithelial Cell Migration Protein Transport Cell Migration Cell Differentiation Epithelial Cell Differentiation Endosome To Melanosome Transport Pigmentation Positive Regulation Of Cell Adhesion Positive Regulation Of Endocytosis Pigment Granule Maturation Pigment Cell Differentiation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane	Platelet degranulation Neutrophil degranulation
Drugs
Diseases
GWAS			Advanced age-related macular degeneration ( 26691988) Cardiac Troponin-T levels ( 31014085) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: APP CD63 ECSIT HRAS NOS3 OGT RAD23A	18 interacting genes: AP4M1 CD82 CD9 F2RL1 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SLC22A1 SLC22A2 SRF TIMP1 TMEM80 VKORC1
Entrez ID		55361	967
HPRD ID		11431	01121
Ensembl ID		ENSG00000155252	ENSG00000135404
Uniprot IDs		Q9BTU6	P08962
PDB IDs		4HND 4HNE 4PLA 4YC4 5EUT 5I0N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Migration Regulation Of Locomotion Regulation Of Cell Motility Endosome Lumen Positive Regulation Of Receptor Internalization Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Biological Quality Protein-containing Complex Positive Regulation Of Signal Transduction Intracellular Signal Transduction Positive Regulation Of Cell Communication Regulation Of Glycolytic Process Intracellular Signaling Cassette Response To Stress Positive Regulation Of Signaling Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Neuronal Synaptic Plasticity Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Amylin Binding Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Type II Interferon Production Regulation Of Protein Catabolic Process Regulation Of Metal Ion Transport Regulation Of Receptor Internalization Glial Cell Development Pigment Granule Maturation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Monoatomic Ion Transport Regulation Of Purine Nucleotide Metabolic Process Regulation Of Potassium Ion Transport Regulation Of MiRNA Metabolic Process Negative Regulation Of Multicellular Organismal Process Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression Positive Regulation Of JNK Cascade Lipoprotein Particle Positive Regulation Of Protein Import GTPase Complex Smooth Muscle Hyperplasia Negative Regulation Of Muscle Hyperplasia	Myoblast Fusion Involved In Skeletal Muscle Regeneration Positive Regulation Of Extracellular Exosome Assembly Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Regulation Of Extracellular Exosome Assembly Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Membrane Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Skin Morphogenesis Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Positive Regulation Of Exocytosis Peptide Antigen Assembly With MHC Class II Protein Complex Positive Regulation Of Exosomal Secretion MHC Class II Protein Complex Neurotransmitter Transmembrane Transporter Activity Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Regulation Of Exosomal Secretion Regulation Of Body Fluid Levels Dopamine Transport Neurotransmitter Reuptake Xenobiotic Transmembrane Transporter Activity MHC Class II Protein Complex Binding Regulation Of Cell Migration Myoblast Fusion Monoamine Transport
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