PI4K2A

Description		phosphatidylinositol 4-kinase type 2 alpha
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GO Annotations	Cellular Component	Golgi Membrane Mitochondrion Lysosomal Membrane Endosome Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Endosome Membrane Membrane Dendrite BLOC-1 Complex Cytoplasmic Vesicle Early Endosome Membrane Growing Cell Tip Presynaptic Membrane Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Membrane Raft Synapse Presynaptic Active Zone Glutamatergic Synapse
	Molecular Function	Nucleotide Binding Magnesium Ion Binding 1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity AP-3 Adaptor Complex Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Golgi Organization Endosome Organization Phosphatidylinositol Phosphate Biosynthetic Process
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: APP CD63 ECSIT HRAS NOS3 OGT RAD23A
Entrez ID		55361
HPRD ID		11431
Ensembl ID		ENSG00000155252
Uniprot IDs		Q9BTU6
PDB IDs		4HND 4HNE 4PLA 4YC4 5EUT 5I0N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cell Migration Regulation Of Locomotion Regulation Of Cell Motility Endosome Lumen Positive Regulation Of Receptor Internalization Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Biological Quality Protein-containing Complex Positive Regulation Of Signal Transduction Intracellular Signal Transduction Positive Regulation Of Cell Communication Regulation Of Glycolytic Process Intracellular Signaling Cassette Response To Stress Positive Regulation Of Signaling Positive Regulation Of Receptor-mediated Endocytosis Regulation Of Neuronal Synaptic Plasticity Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of Carbohydrate Catabolic Process Amylin Binding Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Type II Interferon Production Regulation Of Protein Catabolic Process Regulation Of Metal Ion Transport Regulation Of Receptor Internalization Glial Cell Development Pigment Granule Maturation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Monoatomic Ion Transport Regulation Of Purine Nucleotide Metabolic Process Regulation Of Potassium Ion Transport Regulation Of MiRNA Metabolic Process Negative Regulation Of Multicellular Organismal Process Acetylcholine Receptor Activator Activity Positive Regulation Of Gene Expression Positive Regulation Of JNK Cascade Lipoprotein Particle Positive Regulation Of Protein Import GTPase Complex Smooth Muscle Hyperplasia Negative Regulation Of Muscle Hyperplasia
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