CD63 and TMEM80

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CD63	TMEM80
Description		CD63 molecule	transmembrane protein 80
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Multivesicular Body Plasma Membrane Cell Surface Endosome Membrane Membrane Platelet Dense Granule Membrane Late Endosome Membrane Endosome Lumen Vesicle Multivesicular Body Membrane Protein-containing Complex Azurophil Granule Membrane Melanosome Extracellular Exosome Multivesicular Body, Internal Vesicle	Cilium Membrane Ciliary Transition Zone Cell Projection
	Molecular Function	Protein Binding Protein-containing Complex Binding	Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Cell-matrix Adhesion Negative Regulation Of Epithelial Cell Migration Protein Transport Cell Migration Cell Differentiation Epithelial Cell Differentiation Endosome To Melanosome Transport Pigmentation Positive Regulation Of Cell Adhesion Positive Regulation Of Endocytosis Pigment Granule Maturation Pigment Cell Differentiation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Integrin-mediated Signaling Pathway	Non-motile Cilium Assembly
Pathways		Platelet degranulation Neutrophil degranulation
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Cardiac Troponin-T levels ( 31014085) Refractive error ( 32231278)
Interacting Genes		18 interacting genes: AP4M1 CD82 CD9 F2RL1 GLP1R HLA-DMB HLA-DRA ITGA6 PI4K2A PTGFRN SDC1 SDCBP SLC22A1 SLC22A2 SRF TIMP1 TMEM80 VKORC1	65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4
Entrez ID		967	283232
HPRD ID		01121	14143
Ensembl ID		ENSG00000135404	ENSG00000177042
Uniprot IDs		P08962	A0A0A0MTU4 A0AAA9X375 E9PQJ9 Q96HE8
PDB IDs
Enriched GO Terms of Interacting Partners?		Myoblast Fusion Involved In Skeletal Muscle Regeneration Positive Regulation Of Extracellular Exosome Assembly Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity Acetylcholine Transmembrane Transporter Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Regulation Of Extracellular Exosome Assembly Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Polyamine Transmembrane Transport Membrane Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Skin Morphogenesis Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport Positive Regulation Of Exocytosis Peptide Antigen Assembly With MHC Class II Protein Complex Positive Regulation Of Exosomal Secretion MHC Class II Protein Complex Neurotransmitter Transmembrane Transporter Activity Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Regulation Of Exosomal Secretion Regulation Of Body Fluid Levels Dopamine Transport Neurotransmitter Reuptake Xenobiotic Transmembrane Transporter Activity MHC Class II Protein Complex Binding Regulation Of Cell Migration Myoblast Fusion Monoamine Transport	Membrane Plasma Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Binding
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